Results 71 to 80 of about 514,735 (343)

Targeting Myeloid-Derived Suppressor Cells to Bypass Tumor-Induced Immunosuppression

Frontiers in Immunology, 2018
The immune system has many sophisticated mechanisms to balance an extensive immune response. Distinct immunosuppressive cells could protect from excessive tissue damage and autoimmune disorders.
Viktor Fleming, Xiaoying Hu, Rebekka Weber, V. Nagibin, Christopher Groth, P. Altevogt, J. Utikal, V. Umansky   +7 more
semanticscholar   +1 more source

Heterogeneity of Rheumatoid Arthritis‐Associated Interstitial Lung Disease by Longitudinal Forced Vital Capacity Trajectory and Associations with Disease Outcomes

Arthritis Care &Research, Accepted Article.
Objective We aimed to identify unique disease trajectories within rheumatoid arthritis‐associated interstitial lung disease (RA‐ILD) based on longitudinal forced vital capacity (FVC) values and their associated clinical outcomes. Methods We performed a cohort study of RA‐ILD within the Veterans Health Administration from 1999‐2021. RA‐ILD patients were
Bryant R. England, Yangyuna Yang, Punyasha Roul, Tate M. Johnson, Scott M. Matson, Grant W. Cannon, Brian C. Sauer, Jeffrey R. Curtis, Joshua F. Baker, Ted R. Mikuls   +9 more
wiley   +1 more source

Cost of lifetime immunosuppression coverage for kidney transplant recipients. [PDF]

, 2008
On January 1, 2000, Medicare extended the coverage of immunosuppression medications from 3 years to life for elderly and disabled kidney transplant recipients.
Page, Timothy F, Woodward, Robert
core   +1 more source

Strategies to Design and Optimize Artificial Antigen‐Presenting Cells for T Cell Expansion in Cancer Immunotherapy

Advanced Functional Materials, EarlyView.
This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley   +1 more source

Differential Compartmentalization of Enzymatic Reactions for Lactate Signaling Across Protocells

Advanced Functional Materials, EarlyView.
Two populations of protocells consisting of giant unilamellar vesicles containing active species and distinct artificial organelles are competent of collective behavior by mimicking production, intercellular communication, and detection of the bioinspired signal molecule lactate. Enzymatic cascade reactions within artificial organelles demonstrate that
Arianna Balestri, Xinan Huang, Emanuel Lörtscher, Cora‐Ann Schoenenberger, Cornelia G. Palivan   +4 more
wiley   +1 more source

Clinical trial of FK 506 immunosuppression in adult cardiac transplantation [PDF]

, 1992
The new immunosuppressive agent FK 506 was used as primary immunotherapy in conjunction with low-dose steroids and azathioprine in 72 patients subsequent to orthotopic cardiac transplantation.
Armitage, Bartley P. Griffith, Billingham, Dew, Fung, Gary C. Marrone, John Fung, John M. Armitage, Kormos, Kusne, Robert L. Hardesty, Robert L. Kormos, Shigeki Morita, Starzl, Starzl, Tamura, Thomas E. Starzl, Todo   +17 more
core   +1 more source

A nanovaccine for antigen self-presentation and immunosuppression reversal as a personalized cancer immunotherapy strategy

Nature Nanotechnology, 2022
Chao Liu, Xue Liu, Xinchu Xiang, Xin Pang, Siyuan Chen, Yunming Zhang, En Ren, Lili Zhang, Xuan Liu, Peng Lv, Xiaoyong Wang, Wen-xin Luo, N. Xia, Xiaoyuan Chen, Gang Liu   +14 more
semanticscholar   +1 more source

Dexamethasone-induced immunosuppression: mechanisms and implications for immunotherapy

Journal of Immunotherapy for Cancer, 2018
BackgroundCorticosteroids are routinely utilized to alleviate edema in patients with intracranial lesions and are first-line agents to combat immune-related adverse events (irAEs) that arise with immune checkpoint blockade treatment.
Amber J. Giles, Marsha-Kay N. D. Hutchinson, H. Sonnemann, Jinkyu Jung, Peter E. Fecci, Nivedita M. Ratnam, Wei Zhang, Hua Song, R. Bailey, Dionne L Davis, Caitlin M. Reid, Deric M. Park, M. Gilbert   +12 more
semanticscholar   +1 more source

Metal Nanoclusters for Cancer Imaging and Treatment

Advanced Functional Materials, EarlyView.
This review aims to provide a comprehensive summary and discussion of the core–shell design capabilities of metal nanoclusters (NCs) at the atomic level for cancer imaging and treatment. It offers essential insights into the design principles of metal NCs while also encouraging the exploration of other nanomaterials and their potential theranostic ...
Haiguang Zhu, Ziping Wang, Qiaofeng Yao, Ping Zhang, Jianping Xie, Xun Yuan   +5 more
wiley   +1 more source

Intestinal transplantation [PDF]

, 1994
Intestinal transplantation is often the only alternative form of treatment for patients dependent on total parenteral nutrition for survival.
Andreas G. Tzakis, M.D, Deltz E, Murase N, Satoru Todo, M.D, Starzl TE, Starzl TE, Starzl TE, Thomas E. Starzl, M.D., Ph.D, Todo S, Tzakis AG   +9 more
core   +1 more source