Results 121 to 130 of about 269,737 (365)

Mechanical Interactions Impact the Functions of Immune Cells and Their Application in Immunoengineering

Advanced Therapeutics, EarlyView.
This review covers the mechanical forces experienced by immune cells through cell–cell and cell–extracellular matrix interactions and how these forces influence their receptors and functions. These relationships between forces and cellular functions can be exploited using engineering techniques to modify the physical properties of materials for novel ...
Yu‐Chang Chen, Nghi M. Tran, Kyle H. Vining   +2 more
wiley   +1 more source

Emergence of SARS-CoV-2 with Dual-Drug Resistant Mutations During a Long-Term Infection in a Kidney Transplant Recipient [Corrigendum]

Infection and Drug Resistance
Tanino Y, Nishioka K, Yamamoto C, et al. Infect Drug Resist. 2024:17:531–541. Our authors have advised that there are two sentences that needed revision in the abstract section of the published paper.
Tanino Y, Nishioka K, Yamamoto C, Watanabe Y, Daidoji T, Kawamoto M, Uda S, Kirito S, Nakagawa Y, Kasamatsu Y, Kawahara Y, Sakai Y, Nobori S, Inaba T, Ota B, Fujita N, Hoshino A, Nukui Y, Nakaya T   +18 more
doaj  

Clinical predictors of physiologic change after treatment with immunosuppression in hypersensitivity pneumonitis.

PLoS ONE
IntroductionTreatment of hypersensitivity pneumonitis involves removal of the antigen and may include the use of immunosuppression or antifibrotic therapy.
Margaret Kypreos, Esther de Boer, Graham Ellington, Genichiro Fujioka, Jerry Liu, Craig Glazer, Traci Adams   +6 more
doaj   +1 more source

Microphysiological Systems in Cancer Research: Advancing Immunotherapy through Tumor Microenvironment‐Integrated Organ‐On‐Chip Models

Advanced Therapeutics, EarlyView.
Emerging microphysiological systems reproduce the spatial, biochemical, and cellular complexity of the tumor microenvironment, surpassing 2D cultures and murine models. By integrating patient‐derived tumors, perfusable vasculature, and immune trafficking, these organ‐on‐chip platforms reveal mechanisms of immune evasion, predict therapeutic responses ...
Fabiana Moresi, Francesco Noto, Jyothsna Vasudevan, Xavier Bisteau, Giulia Adriani, Andrea Pavesi   +5 more
wiley   +1 more source

Cytokine Engineering Approaches for Regenerative Medicine

Advanced Therapeutics, EarlyView.
Engineered cytokines represent a powerful strategy to promote tissue repair and regeneration by precisely modulating immune responses. This review highlights recent advances in cytokine engineering, including strategies to enhance half‐life, improve tissue and cell targeting, and control receptor signaling.
Shiyi Li, Wenhao You, Mikaël M. Martino
wiley   +1 more source

Risks and benefits of weaning immunosuppression in liver transplant recipients: Long-term follow-up [PDF]

, 1997
Flynn, B, Fung, JJ, Marino, I, Mazariegos, GV, Reyes, J, Starzl, IE   +5 more
core   +1 more source

1948: Camapth-1H as Induction Therapy Allows Steroids-Free Maintenance Immunosuppression in Renal Transplantation [PDF]

, 2004
Gaetano Ciancio, George Burke, Jeffrey J. Gaynor, Adela Mattiazzi, Anne Rosén, Anil Vaidya, M. Carmen Carreño, Ramin Roohipour, Joshua Miller   +8 more
openalex   +1 more source

Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy

Advanced Therapeutics, EarlyView.
This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar, Weiwei Guo, Xin Shen, Yimeng Fang, Yilin Liu, Peng‐Yuan Wang, Roey Elnathan, Yaping Chen   +7 more
wiley   +1 more source

SMYD3 Promotes Immune Evasion in Clear Cell Renal Cell Carcinoma via SREBP1‐Mediated Transactivation of CD47

Advanced Science, EarlyView.
Cancer cell‐intrinsic SMYD3 orchestrates an immunosuppressive microenvironment and impairs the response to PD‐1 blockade by reprogramming immune cells landscape in the tumor microenvironment of clear cell renal cell carcinoma (ccRCC). The immunomodulatory function of SMYD3 is mediated via the SREBP1/CD47 pathway.
Zhengfang Liu, Xiumei Zhao, Maolin Zang, Huiyang Yuan, Xin Qin, Xiaofeng Li, Shuo Zhao, Ruirong Tan, Keqiang Yan, Li Liu, Yidong Fan, Ning Zhang, Benkang Shi, Bo Han, Shouzhen Chen   +14 more
wiley   +1 more source

Identification and external validation of IgA nephropathy patients benefiting from immunosuppression therapy. [PDF]

EBioMedicine, 2020
Chen T, Xia E, Chen T, Zeng C, Liang S, Xu F, Qin Y, Li X, Zhang Y, Liang D, Xie G, Liu Z.   +11 more
europepmc   +1 more source