Results 101 to 110 of about 215,011 (302)

Gardiquimod Nanoemulsion Targets Cutaneous Leishmaniasis Lesions Reducing Systemic Toxicity and Parasite Burden

Advanced Healthcare Materials, EarlyView.
Nanoemulsion delivery of a TLR7 agonist enhances safety and promotes colocalization with Leishmania‐infected macrophages in skin lesions, enabling a ∼2‐log reduction in parasite burden. However, tissue‐level constraints and TLR‐driven regulatory feedback generate a mixed immune response that limits complete parasite clearance.
Carmen Palomino‐Cano, M. Carmen Mera‐Delgado, Esther Moreno, Esther Larrea, Lecnia Aguirre, Jonathan Miguel Zanatta, Sónia Barros‐Carvalho, Iola F. Duarte, Ricardo Silvestre, Juan M. Irache, Javier Carrión, Socorro Espuelas   +11 more
wiley   +1 more source

Successful rescue of fulminant myocarditis with mechanical circulatory support and immunosuppression therapy: A case report. [PDF]

Front Cardiovasc Med, 2023
Zhou C.
europepmc   +1 more source

Overcoming skin rejection in composite tissue allotransplantation [PDF]

, 2008
The application of composite tissue techniques is constrained by the susceptibility of skin to rejection. The aim of this thesis is to improve our understanding of skin rejection and find ways to avoid it, in order to enable expansion of the ...
Horner, B., Horner, R.
core  

Blockade of PD-1 immunosuppression boosts CAR T-cell therapy [PDF]

, 2023
Blockade of PD-1 immunosuppression boosts CAR T-cell ...
Phillip K Darcy (13533889), Liza B John (13533970), Michael H Kershaw (13533892)   +2 more
core  

Immunosuppression Therapy in Acquired Hemophilia A: Pursuing an Optimal Regimen. [PDF]

Cureus, 2021
Teixeira Passos D, Abrantes AM, Santos L, Cardoso A, Pais de Lacerda A.   +4 more
europepmc   +1 more source

Temporal Immune and Metabolic Shifts Drive the Anti‐Tumor Efficacy of Resiquimod‐Loaded Nanoparticles in Peritoneal Carcinomatosis

Advanced Healthcare Materials, EarlyView.
Peritoneal carcinomatosis is a hard‐to‐treat spread of abdominal cancers that often returns after therapy. Nanoparticles were developed to retain an immune‐boosting drug in the abdomen. When combined with chemotherapy in mice, this approach eliminated tumors in many cases and prevented recurrence, helping the immune system mount a stronger, longer ...
Vanessa Chan, Po‐Han Chao, XuXin Sun, Jun Han, Sarah MacPherson, Lucas J. Andrew, Noah Y. Brittain, Tien Do, Marcel B. Bally, Julian J. Lum, Shyh‐Dar Li   +10 more
wiley   +1 more source

Humoral Response After SARS-CoV-2 Vaccination in Kidney Transplant Recipients: Role of Immunosuppression Therapy. [PDF]

Transplant Proc, 2022
López V, Polo C, Schuldt R, Vázquez T, Gutiérrez-Vílchez E, Moliz C, Hernández D.   +6 more
europepmc   +1 more source

Reprogramming the Immunosuppressive Microenvironment in Triple‐Negative Breast Cancer via FAP‐Targeted Nanoprobes for Multimodal Imaging and Photothermal Therapy

Advanced Materials, EarlyView.
Targeting cancer‐associated fibroblasts (CAFs) with fibroblast activation protein (FAP)‐directed nanoprobes for multimodal imaging and photothermal remodeling of the immunosuppressive microenvironment to enhance immunotherapy in triple‐negative breast cancer (TNBC).
Ling Zhan, Yanhong Chen, Jingjing Hu, Chunting Wang, Huanhuan Liu, Defan Yao, Dengbin Wang   +6 more
wiley   +1 more source

Therapy-related issues: malignant diseases and immunosuppression [PDF]

, 2017
This chapter outlines information relevant to clinical pharmacists related to malignant disease and immunosuppression and is loosely based on the British National Formulary, Chapter 8.
Marc Mitchell, Nicola Stoner, Melanie Snelling, Philip Wiffen   +3 more
core   +1 more source

Living donor liver transplantation for autoimmune hepatitis in identical monozygotic twins: a case report

Clinical Transplantation and Research
Liver transplantation (LT) is an effective treatment for end-stage liver diseases, including autoimmune hepatitis. Advances in immunosuppressive therapy have improved patient and graft survival; however, these treatments can cause serious side effects ...
Kulbhushan Haldeniya, Kausar Makki, Yogesh Yadav, Tathagata Karan, Nalini Kanta Ghosh, Piyush Srivastava, Anil Agarwal, Vivek Vij   +7 more
doaj   +1 more source