Results 91 to 100 of about 215,011 (302)

Individualizing immunosuppression in lung transplantation [PDF]

, 2018
Immunosuppression management after lung transplantation continues to evolve, with an increasing number of agents available for use in various combinations allowing for more choice and individualization of immunosuppressive therapy.
Jennifer K McDermott, Reda E Girgis
core   +1 more source

Safety of Prescription Nonsteroidal Anti‐inflammatory Drugs in Adults With Inflammatory Bowel Disease: Data From a Large Administrative Claims Cohort

Arthritis Care &Research, EarlyView.
Objective The concern that nonsteroidal anti‐inflammatory drugs (NSAIDs) may precipitate flares of inflammatory bowel disease (IBD) has limited their use in managing musculoskeletal symptoms in those with IBD, but safety data are mixed. Methods This retrospective cohort study included patients with IBD aged at least 18 years from Optum's deidentified ...
Adam S. Mayer, Rui Xiao, Meenakshi Bewtra, Michael D. George, Pamela F. Weiss   +4 more
wiley   +1 more source

Race and Household Income Are Associated With Disease Outcomes in Pediatric Patients With Antineutrophil Cytoplasmic Antibody–Associated Vasculitis Hospitalized in the United States

Arthritis Care &Research, EarlyView.
Objective Race and household income impact outcomes in patients with rheumatic conditions; however, their role in pediatric antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV) remains poorly understood. We aimed to evaluate whether race and ethnicity and household income are associated with severe AAV disease and renal outcomes among
Roberto Alejandro Valdovinos, William Daniel Soulsby III, Emily von Scheven   +2 more
wiley   +1 more source

Immunosuppressive Drug Use in Limited Systemic Sclerosis: An International Survey

Arthritis Care &Research, EarlyView.
Objective Current guidelines recommend immunosuppressive treatment for diffuse cutaneous systemic sclerosis but are less clear on their use in limited cutaneous systemic sclerosis (lcSSc) in the absence of internal organ complications. We conducted an international survey to understand current immunosuppressive drug prescribing patterns in lcSSc ...
Sabrina Hoa, Yicheng Mu, Marie Hudson, Janet Pope   +3 more
wiley   +1 more source

The impact of pharmacists’ interventions within the closed loop immunosuppressant management process on kidney transplant recipients: a retrospective cohort study

Frontiers in Immunology
IntroductionNowadays, kidney transplant recipients’ primary challenge is improving graft function. However, they are rarely provided effective long-term instructions on immunosuppressant use after transplant.
Hongxia Chen, Chuan Li, Shengsong Ou, Xiaoyu Chen   +3 more
doaj   +1 more source

Caregiver Perspectives on the Burden of Disease and Treatment in Uncontrolled Gout

Arthritis Care &Research, Accepted Article.
Objective Uncontrolled gout (UG) refers to persistently elevated serum urate (SU) levels >6 mg/dL and ongoing gout symptoms despite use of urate‐lowering therapy (ULT). The objective of this study was to evaluate the burden associated with informal caregiving for individuals with UG.
Angelo Gaffo, Bhavisha Desai, Abiola Oladapo, Nana Kragh, Rebekah Zincavage, Brad Padilla, Naomi Schlesinger   +6 more
wiley   +1 more source

Open-label comparative clinical study of chlorproguanil−dapsone fixed dose combination (Lapdap™) alone or with three different doses of artesunate for uncomplicated plasmodium falciparum malaria [PDF]

, 2008
The objective of this study was to determine the appropriate dose of artesunate for use in a fixed dose combination therapy with chlorproguanil−dapsone (CPG−DDS) for the treatment of uncomplicated falciparum ...
Peter A Winstanley, Nyirenda, Maggie, Kanjala, Maxwell K., Molyneux, Malcolm, Sam Dunyo, Stephan Duparc, Paula L Kirby, Winstanley Peter A., Kirby, Paula L., Blencowe, Hannah, Daniel G Wootton, Woessner, Mary, Thomas Kanyok, Stephen Ward, Opara, Hyginus, Molyneux Malcolm, Winstanley, Peter A, Wootton Daniel G., Maggie Nyirenda, Ward, Stephen, Dunyo, Sam, Giancarlo A Biagini, Kanjala, Maxwell K, Nyirenda Maggie, Kanyok Thomas, Maxwell K Kanjala, Opara Hyginus, Duparc, Stephan, Kanyok, Thomas, Queen Dube-Mbeye, Duparc Stephan, Malcolm Molyneux, Neate, Colin, Biagini, Giancarlo A, Biagini Giancarlo A., Ward Stephen, Kirby Paula L., Wootton, Daniel G., Wootton, Daniel G, Kirby, Paula L, Hannah Blencowe, Mary Woessner, Kanjala Maxwell K., Molyneux, Malcolm E., Biagini, Giancarlo A., Woessner Mary, Dube-Mbeye Queen, Colin Neate, Hyginus Opara, Neate Colin, Blencowe Hannah, Dunyo Sam, Winstanley, Peter, Dube-Mbeye, Queen   +53 more
core   +1 more source

Gellan Gum Fluid Gel System for Controlled‐Delivery of Cytokine‐Licensed MSC‐EVs to Enhance Corneal Repair in Limbal Stem Cell Deficiency

Advanced Healthcare Materials, EarlyView.
Gellan gum fluid gel (FG) enables controlled ocular delivery of mesenchymal stromal cell (MSC)‐derived extracellular vesicles (EV). Its shear‐thinning, solid‐liquid‐solid rheology ensures prolonged ocular retention. Sustained MSC‐EV release (∼18% in 6 hrs) supports effective EV ocular delivery.
Seyedmohammad Moosavizadeh, Ava Dashti, Thomas E. Robinson, Robyn Gaffey, Richard Moakes, Neil Lagali, Liam Grover, Thomas Ritter   +7 more
wiley   +1 more source

Perinatal Management of Neuromyelitis Optica Spectrum Disorder in Pregnancy: A Case Report

International Journal of Women's Health
Jue Wang, Rong Hu, Hao Zhu Department of Obstetrics, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, People’s Republic of ChinaCorrespondence: Hao Zhu, Department of Obstetrics, the Obstetrics and Gynecology Hospital of Fudan University,
Wang J, Hu R, Zhu H
doaj  

Guiding immunotherapy based on the oxford classification activity score in IgA nephropathy

Frontiers in Endocrinology
BackgroundThe efficacy of Oxford classification in guiding immunotherapy management strategies remains a subject of debate. Our study aimed to explore different combinations of Oxford Classification activity scores in guiding immunotherapy for IgA ...
Jingjing Nong, Yuhong Tang, Jiazhen Yang, Wenli Wei, Licong Su, Sheng Nie, Jun Ou   +6 more
doaj   +1 more source