Results 121 to 130 of about 213,546 (300)

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

Tailoring immunosuppressive therapy [PDF]

Nephrology Dialysis Transplantation, 2002
Dirk R J, Kuypers, Y C, Vanrenterghem
openaire   +2 more sources

Modern immunosuppression

, 2014
Organ transplantation provides both life-saving and life-enhancing function for patients suffering from end-stage organ failure. Transplantation has only been possible due to the advances in immunosuppression.
Wilson C, Figueiredo RS
core  

Periodontal Indices in Patients with Rheumatoid Arthritis Undergoing Immunosuppressive Therapy [PDF]

مجله دانشگاه علوم پزشکی گرگان
Background and Objective: Periodontitis and rheumatoid arthritis are two chronic inflammatory diseases that are interrelated. Given the similarities between these conditions, the medications used by patients with rheumatoid arthritis (RA) may affect ...
Ilnaz Frahoudi, Afsaneh Enteshari-Moghaddam, Zakiyeh Movahedzadeh   +2 more
doaj  

Treatment-resistant inflammatory demyelinating pseudotumor with Marburg-like features: A narrative review-based treatment approach

Journal of Research in Medical Sciences
Inflammatory demyelinating pseudotumor (IDP) mimics intracranial neoplasms in terms of both clinical presentation and imaging features. IDP with Marburg-like features represents a severe form of inflammatory demyelinating encephalomyelitis, marked by a ...
Mohammad Amin Najafi, Shakiba Houshi, Payam Riahi, Salar Nasr, Mohammad Reza Najafi   +4 more
doaj   +1 more source

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

Advanced Science, EarlyView.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang, Yaning Li, Jianxun Cai, Lisi Luo, Pengfei Yang, Yutong Chen, Jiancong Zhou, Yan Zeng, Jiaping Yu, Weiyu Zhang, Wenzheng Pang, Yufang Li, Chunhua Wen, Jian Li, Linjuan Zeng   +14 more
wiley   +1 more source

Immunosuppression

Immunosuppression in LTRs is largely based on experience of immunosuppression from recipients with other types of SOT. Triple immunosuppressive therapy with a CNI, an antimetabolite and corticosteroids is the standard of care after LTx.
Gerovasili, Vicky, Perch, Michael, Bos, Saskia   +2 more
core   +1 more source

Pneumocystis and Herpesviruses in Immunocompromised Children [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2015
Objective. Objectives. Study of the role of herpes viruses and pathogen in the etiology of infectious diseases in children with immunosuppression of different nature to provide an adequate etiotropic therapy and prophylaxis of these infections ...
Savinkov P.A., Rybalkina T.N., Karazhas N.V., Kornienko M.N., Kalugina M.Yu., Rusakova E.V., Soldatova I.A., Pchelkina D.S., Krupenio T.V., Tsirulnikova I.E., Silina O.V.   +10 more
doaj  

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Effects of and Predictors for Tacrolimus Rescue Therapy among Renal Transplant Patients under Cyclosporine-Based Immunosuppression

, 2008
BACKGROUND: Though cyclosporine has dramatically decreased rejection rates and improved graft survival rates of renal allografts, there is still a remarkable rate of acute rejection and progressive deterioration of renal function after transplantation ...
HU, REY-HENG;LEE, CHIH-YUAN;TSAI, MENG-KUNG;LEE, PO-HUANG, 胡瑞恆;李志元;蔡孟昆;李伯皇   +1 more
core