Efficacy and Mechanism EvaluationBackground Long-term surviving liver transplant recipients can spontaneously develop operational tolerance, which allows them to completely discontinue their immunosuppression, but we lack validated tools to predict the likelihood of rejection following ...
Julien Vionnet +22 more
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Advances in the Study of Immunosuppressive Mechanisms in Sepsis
Journal of Inflammation Research, 2023 Xuzhe Fu,1 Zhi Liu,2 Yu Wang1 1Department of Emergency Medicine, Shengjing Hospital of China Medical University, Shenyang, People’s Republic of China; 2Department of Ophthalmology, Shengjing Hospital of China Medical University, Shenyang, People’s ...
Fu X, Liu Z, Wang Y
doaj
Results of pancreas transplantation after steroid withdrawal under tacrolimus immunosuppression [PDF]
, 2000 Purpose. The results of steroid withdrawal in pancreas transplant recipients under tacrolimus immunosuppression were analyzed. Methods. From July 4, 1994 until April 30, 1998, 147 pancreas transplantations were performed in 141 patients, including 126 ...
Burke +42 more
core +1 more source
A mathematical model of CAR-T cell therapy in combination with chemotherapy for malignant gliomas [PDF]
arXivWe study the dynamics and interactions between combined chemotherapy and chimeric antigen receptor (CAR-T) cells therapy and malignant gliomas (MG). MG is one of the most common primary brain tumor, with high resistance to therapy and unfavorable prognosis.
arxiv
Mathematical model of CAR-T-cell therapy for a B-cell Lymphoma lymph node [PDF]
arXivCAR-T cell therapies have demonstrated significant success in treating B-cell leukemia in children and young adults. However, their effectiveness in treating B-cell lymphomas has been limited. Unlike leukemia, lymphoma often manifests as solid masses of cancer cells in lymph nodes, glands, or organs, making these tumors harder to access thus hindering ...
arxiv
Scale-free dynamics of somatic adaptability in immune system [PDF]
arXiv, 2009 The long-time dynamics of somatic adaptability in immune system is simulated by a simple physical model. The immune system described by the model exhibits a scale free behavior as is observed in living systems. The balance between the positive and negative feedbacks of the model leads to a robust immune system where the positive one corresponds to the ...
arxiv
Eradication of parvovirus B19 infection after renal transplantation requires reduction of immunosuppression and high-dose immunoglobulin therapy [PDF]
, 2002 Lutz Liefeldt
openalex +1 more source
PLoS ONEIntroductionTreatment of hypersensitivity pneumonitis involves removal of the antigen and may include the use of immunosuppression or antifibrotic therapy.
Margaret Kypreos +6 more
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Anti-Erythropoietin Antibody Associated Pure Red Cell Aplasia Resolved after Liver Transplantation
Case Reports in Transplantation, 2015 Patients undergoing antiviral therapy for chronic hepatitis C often develop anemia secondary to ribavirin and interferon. Recombinant erythropoietin has been used to improve anemia associated with antiviral therapy and to minimize dose reductions, which ...
Annie K. Hung +3 more
doaj +1 more source
Geometric immunosuppression in CAR-T cell treatment: Insights from mathematical modeling [PDF]
arXivChimeric antigen receptor T (CAR-T) cell therapy has emerged as a promising treatment for hematological malignancies, offering a targeted approach to cancer treatment. Understanding the complexities of CAR-T cell therapy within solid tumors poses challenges due to the intricate interactions within the tumor microenvironment.
arxiv