Off-label use of rituximab in dermatology: pemphigus treatment [PDF]
Since its approval in 1997 by the FDA (United States Food and Drug Administration), rituximab has been used for certain B-cell lymphomas and treatment-resistant rheumatoid arthritis.
Lislaine Bomm+4 more
doaj +1 more source
Safety and effectiveness of mycophenolate mofetil associated with tacrolimus for liver transplantation immunosuppression: a systematic review and meta-analysis of randomized controlled trials [PDF]
A combination of immunosuppressants may improve outcomes due to the synergistic effect of their different action mechanisms. Currently, there is no consensus regarding the best immunosuppressive protocol after liver transplantation.
Francisco Tustumi+11 more
doaj +1 more source
Refractory pemphigus vulgaris treated with rituximab and mycophenolate mofetil [PDF]
The main treatment for pemphigus vulgaris are systemic corticosteroids and immunosuppressive agents, but due to adverse reactions and therapeutic failure, new drugs such as rituximab and mycophenolate mofetil have been used.
Stephanie Del Rio Navarrete Biot+5 more
doaj +1 more source
Infiltrative cardiomyopathies. Report of a case of cardiac sarcoidosis
Sarcoidosis is characterized by the presence of non-caseating granulomas that may affect any organ. Heart involvement manifests as cardiomyopathy. Frequency of cardiac involvement in sarcoidosis is around 30 %, but only 5 % of such cases are symptomatic.
Muñoz-Ortiz, Édison+3 more
doaj +1 more source
New drugs, new challenges for dermatologists: mucocutaneous ulcers secondary to everolimus [PDF]
Everolimus, a mammalian target of rapamycin inhibitor, is an emerging drug, which is being increasingly applied in oncology and solid organ transplantation. Oral ulcers are a frequent side effect associated with this immunosupressor.
Victor Pavan Pasin+5 more
doaj +1 more source
Background Immunosuppressive agents have been widely used in the treatment of IgA nephropathy (IgAN), but the efficacy and safety remain controversial.
Zheng Zhang+3 more
doaj +1 more source
Statins as immunosuppressive agents [PDF]
Abstract Unavailable. Please See Print Journal.
openaire +3 more sources
New immunosuppressive agents in pediatric transplantation
Immunosuppressive therapy in pediatrics continues to evolve. Over the past decade, newer immunosuppressive agents have been introduced into adult and pediatric transplant patients with the goal of improving patient and allograft survival.
Christina Nguyen, Ron Shapiro
doaj +1 more source
Imunossupressores na Dermatologia Immunosuppressive agents in Dermatology
Os imunossupressores são drogas que agem na divisão celular e têm propriedades anti-inflamatórias. Sendo assim, são essencialmente prescritos na prevenção de rejeição de transplantes e no tratamento das doenças autoimunes e inflamatórias crônicas, que ...
Aline Lopes Bressan+3 more
doaj +1 more source
Nonimmunologic targets of immunosuppressive agents in podocytes
Proteinuria is a characteristic finding in glomerular diseases and is closely associated with renal outcomes. In addition, therapeutic interventions that reduce proteinuria improve renal prognosis.
Tae-Hyun Yoo, Alessia Fornoni
doaj +1 more source