Results 1 to 10 of about 327,034 (336)
Neoantigen‐reactive T cell: An emerging role in adoptive cellular immunotherapy
MedComm, 2021 Adoptive cellular immunotherapy harnessing the intrinsic immune system for precise treatment has exhibited preliminary success against malignant tumors.
Yicheng Zhu +4 more
doaj +2 more sources
Adoptive Immunotherapy beyond CAR T-Cells [PDF]
Cancers, 2021 Adoptive cell immunotherapy (ACT) is a vibrant field of cancer treatment that began progressive development in the 1980s. One of the most prominent and promising examples is chimeric antigen receptor (CAR) T-cell immunotherapy for the treatment of B-cell hematologic malignancies.
Aygul Rakhmatullina +10 more
openaire +4 more sources
Adoptive T Cell Immunotherapy for Cancer [PDF]
Rambam Maimonides Medical Journal, 2015 Harnessing the immune system to recognize and destroy tumor cells has been the central goal of anti-cancer immunotherapy. In recent years, there has been an increased interest in optimizing this technology in order to make it a clinically feasible ...
Karlo Perica +3 more
doaj +4 more sources
Adoptive immunotherapy for cytomegalovirus infection [PDF]
Journal of Applied Sciences and Environmental Management, 2005 We reported a case with interstitial pneumonia associated with cytomegalovirus (CMV) infection in whom clinical improvement was observed after the treatment with primary adoptive immunotherapy.
M D Kei Numazaki
doaj +3 more sources
OncoImmunology, 2017 Adoptive T cell therapy has emerged as a powerful strategy to treat human cancers especially haematological malignancies. Extension of these therapies to solid cancers remains a significant challenge especially in the context of defining immunological ...
Corey Smith +20 more
doaj +2 more sources
Adoptive cellular immunotherapy for solid neoplasms beyond CAR-T
Molecular Cancer, 2023 In recent decades, immune checkpoint blockade and chimeric antigen receptor T cell (CAR-T) therapy are two milestone achievements in clinical immunotherapy. However, both show limited efficacies in most solid neoplasms, which necessitates the exploration
Qiaofei Liu +8 more
semanticscholar +1 more source
Applied Bionics and Biomechanics, 2022 Objective. To explore the differential efficacy of chemoradiotherapy combined with adoptive immunotherapy and radiochemotherapy alone in patients with non-small-cell lung cancer (NSCLC). Methods.
Zhiming Fan, Honggui He, Liqun Chen
doaj +1 more source
Natural killer cells in antitumour adoptive cell immunotherapy
Nature Reviews. Cancer, 2022 Natural killer (NK) cells comprise a unique population of innate lymphoid cells endowed with intrinsic abilities to identify and eliminate virally infected cells and tumour cells.
Tamara J Laskowski +2 more
semanticscholar +1 more source
Anti-Tumor Effects after Adoptive Transfer of IL-12 Transposon-Modified Murine Splenocytes in the OT-I-Melanoma Mouse Model. [PDF]
PLoS ONE, 2015 Adoptive transfer of gene modified T cells provides possible immunotherapy for patients with cancers refractory to other treatments. We have previously used the non-viral piggyBac transposon system to gene modify human T cells for potential immunotherapy.
Daniel L Galvan +6 more
doaj +1 more source
Nature Communications, 2021 Emerging data demonstrate that the activity of immune cells can be modulated by microbial molecules. Here, we show that the short-chain fatty acids (SCFAs) pentanoate and butyrate enhance the anti-tumor activity of cytotoxic T lymphocytes (CTLs) and ...
Maik Luu +25 more
semanticscholar +1 more source