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Adoptive T Cell Immunotherapy For Cancer [PDF]
Rambam Maimonides Medical Journal, 2015 Harnessing the immune system to recognize and destroy tumor cells has been the central goal of anti-cancer immunotherapy. In recent years, there has been an increased interest in optimizing this technology in order to make it a clinically feasible treatment.
Mathias Oelke +3 more
openaire +5 more sources
Adoptive Immunotherapy in Chimeras with Donor Lymphocytes [PDF]
Acta Haematologica, 2003 Allogeneic stem cell transplantation has a well-defined indication in the treatment of hematological malignancies. The beneficial immune effect of allogeneic marrow transplantation has long been known, but only recently have methods been developed to ...
Chen, Xiao +8 more
core +6 more sources
Adoptive immunotherapy for cytomegalovirus infection [PDF]
Journal of Applied Sciences and Environmental Management, 2005 We reported a case with interstitial pneumonia associated with cytomegalovirus (CMV) infection in whom clinical improvement was observed after the treatment with primary adoptive immunotherapy. Although adoptive transfer of CMV-specific T cells offers the potential for reconstitution of viral immunity after allegoric transplantation, the logistics of ...
M D Kei Numazaki
openaire +4 more sources
Addressing current challenges in cancer immunotherapy with mathematical and computational modeling [PDF]
Journal of the Royal Society Interface, 14 (131): 20170150 (2017), 2017 The goal of cancer immunotherapy is to boost a patient's immune response to a tumor. Yet, the design of an effective immunotherapy is complicated by various factors, including a potentially immunosuppressive tumor microenvironment, immune-modulating ...
Adler, Adam J. +3 more
core +2 more sources
Applied Bionics and Biomechanics, 2022 Objective. To explore the differential efficacy of chemoradiotherapy combined with adoptive immunotherapy and radiochemotherapy alone in patients with non-small-cell lung cancer (NSCLC). Methods.
Zhiming Fan, Honggui He, Liqun Chen
doaj +1 more source
Neoantigenâreactive T cell: An emerging role in adoptive cellular immunotherapy
MedComm, 2021 Adoptive cellular immunotherapy harnessing the intrinsic immune system for precise treatment has exhibited preliminary success against malignant tumors.
Yicheng Zhu +4 more
doaj +1 more source
Anti-Tumor Effects after Adoptive Transfer of IL-12 Transposon-Modified Murine Splenocytes in the OT-I-Melanoma Mouse Model. [PDF]
PLoS ONE, 2015 Adoptive transfer of gene modified T cells provides possible immunotherapy for patients with cancers refractory to other treatments. We have previously used the non-viral piggyBac transposon system to gene modify human T cells for potential immunotherapy.
Daniel L Galvan +6 more
doaj +1 more source
Adoptive immunotherapy in postoperative hepatocellular carcinoma: a systemic review. [PDF]
PLoS ONE, 2012 PURPOSE: The effectiveness of immunotherapy for postoperative hepatocellular carcinoma patients is still controversial. To address this issue, we did a systemic review of the literatures and analyzed the data with emphasis on the recurrence and survival.
Feng Xie +8 more
doaj +1 more source
A novel and effective cancer immunotherapy mouse model using antigen-specific B cells selected in vitro. [PDF]
PLoS ONE, 2014 Immunotherapies such as adoptive transfer of T cells or natural killer cells, or monoclonal antibody (MoAb) treatment have recently been recognized as effective means to treat cancer patients.
Tatsuya Moutai +3 more
doaj +1 more source
Review of precision cancer medicine: Evolution of the treatment paradigm. [PDF]
, 2020 In recent years, biotechnological breakthroughs have led to identification of complex and unique biologic features associated with carcinogenesis. Tumor and cell-free DNA profiling, immune markers, and proteomic and RNA analyses are used to identify ...
Fountzilas, Elena +3 more
core +1 more source