Molecular theranostics: principles, challenges and controversies
Molecular theranostics offers a powerful tool to drive precision medicine in nuclear oncology. While theranostics is not a new principle in nuclear medicine, recent advances in instrumentation and radiopharmacy have driven a reinvigoration and a broader suite of applications.
Geoffrey Currie
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Complete metabolic response as early predictor of long-term efficacy after adoptive T cell therapy using tumor-infiltrating lymphocytes. [PDF]
Borch TH+5 more
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ABSTRACT Background and Objectives IO has transformed cancer management, but its adoption in advanced cancer patients varies by tumor type. With more Stage IV patients undergoing surgery, understanding site‐specific outcomes in these challenging patients is essential.
Samantha C. Warwar+4 more
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Novel research model for in vitro immunotherapy: co-culturing tumor organoids with peripheral blood mononuclear cells. [PDF]
Li P, Huang M, Ma Y, Zhang Y, Shi C.
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CT Scans Understage Lymph Nodes in Gastric and Gastroesophageal Adenocarcinoma
ABSTRACT Background and Objectives The presence of lymph node metastases in patients with gastric and gastroesophageal junction (GEJ) adenocarcinoma provides prognostic information and guides treatment decisions. We sought to determine the sensitivity of computed tomography (CT) imaging for clinical nodal staging in patients with resectable gastric and
Morgan F. Pettigrew+6 more
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Immunotherapy in nasopharyngeal carcinoma: current status and unanswered questions. [PDF]
Liu X, Ma J.
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ABSTRACT Background and Objectives The American Urological Association (AUA) guidelines recommend evaluating asymptomatic microhematuria (MH) at ≥ 3 red blood cells per high powered field (RBCs/hpf), resulting in significant costs with limited bladder cancer detections.
Krishay Sridalla+6 more
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Differential regulation of calcium-NFAT signaling pathway by Akt isoforms: unraveling effector dynamics and exhaustion of cytotoxic T lymphocytes in tumor microenvironment. [PDF]
Chen WL+6 more
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Immune cell infiltration into brain tumor microenvironment is mediated by Rab27-regulated vascular wall integrity. [PDF]
Adnani L+6 more
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HPV-driven cancers: a looming threat and the potential of CRISPR/Cas9 for targeted therapy. [PDF]
Kermanshahi AZ+4 more
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