Results 51 to 60 of about 44,698 (259)
Genetically Modified T-Cell-Based Adoptive Immunotherapy in Hematological Malignancies
Journal of Immunology Research, 2017 A significant proportion of hematological malignancies remain limited in treatment options. Immune system modulation serves as a promising therapeutic approach to eliminate malignant cells.
Baixin Ye +7 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan +5 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi +5 more
wiley +1 more source
Cancer Immunotherapy Based on Natural Killer Cells: Current Progress and New Opportunities
Frontiers in Immunology, 2019 Cancer immunotherapy has been firmly established as a new milestone for cancer therapy, with the development of multiple immune cells as therapeutic tools.
Weilei Hu +6 more
doaj +1 more source
Hydrogel Microtube Drug Carrier for Catheter‐Based Intravascular Therapy
Advanced Healthcare Materials, EarlyView.This paper proposes hydrogel microtube carriers composed of barium alginate gel, enabling long‐term vascular retention without interrupting blood flow. Intravascular treatments have long been attracting attention for therapeutic efficacy, yet practical delivery methods remained unestablished.
Shota Sato +8 more
wiley +1 more source
Nanoparticle Drug Delivery Systems Designed to Improve Cancer Vaccines and Immunotherapy
Vaccines, 2015 Recent studies have demonstrated great therapeutic potential of educating and unleashing our own immune system for cancer treatment. However, there are still major challenges in cancer immunotherapy, including poor immunogenicity of cancer vaccines, off ...
Yuchen Fan, James J. Moon
doaj +1 more source
Adoptive immunotherapy for myeloid malignancies [PDF]
Leukemia Supplements, 2014 In allogeneic stem cell transplantation (allo-SCT), much of the anti-tumor effect is derived from a graft versus tumor (GVT) response that is dependent on donor cell engraftment. In order to attain engraftment large doses of chemotherapy are administered to suppress the host's immune system.
openaire +2 more sources
Advanced Materials, EarlyView.Controlling the protein corona formation onto carbon nanomaterials (CNMs) enhances their functionalities as platforms for cancer theranostics. Here, we reviewed the effects of the intrinsic and acquired properties of CNMs on protein corona formation, the consequent biological and toxicological outcomes, and the strategies to reshape corona formation ...
Yajuan Zou +5 more
wiley +1 more source
Phase Engineering of Nanomaterials (PEN): Evolution, Current Challenges, and Future Opportunities
Advanced Materials, EarlyView.This review summarizes the synthesis, phase transition, advanced characterization spanning ex situ to in situ and operando techniques, and diverse applications of phase engineering of nanomaterials (PEN). It further outlines key challenges and future opportunities, such as phase stability, architecture control, and artificial intelligence (AI)‐driven ...
Ye Chen +7 more
wiley +1 more source
Establishment of whole tumor cell antigen-induced cellular immunotherapy for lung adenocarcinoma
OncologieAlthough immunotherapy improves the prognosis of many current advanced malignancies, many patients still do not respond or develop resistance after immunotherapy.
Zhu Binghan +6 more
doaj +1 more source