Results 91 to 100 of about 786,579 (199)

Cancer vaccines: uses of HLA transgenic mice compared to genetically modified mice [PDF]

, 2008
Many tumor antigens have been identified that can be targeted by the immune system. Animal models that have been genetically modified to express human HLA molecules instead of their own MHC antigens have shown to be valuable in the discovery of peptides ...
McArdle, SE
core  

Are the elderly from India different from the rest of the world? Data in patients with cancer on immunotherapy

, 2021
Amish D. Vora
openalex   +1 more source

Attenuation of natural killer cell cytotoxicity by interaction between NKp30 of NK cells and dipeptidase 1 of colon cancer cells

Scientific Reports
Natural killer (NK) cells play a crucial role in immune surveillance by recognizing and eliminating tumor cells. However, tumors employ various mechanisms to evade NK cell-mediated immunity.
Jong-Tae Kim, Eun Sun Park, Yo Sep Hwang, Hyang Ran Yoon, Suk Ran Yoon, Hee Jun Cho, Hee Gu Lee   +6 more
doaj   +1 more source

Gestational hypothyroxinemia causes an inflammatory environment at maternal-fetal tissues and fetal brain with impaired hippocampal dendritic spine maturation in the offspring

Scientific Reports
Gestational hypothyroxinemia (HTX) is associated with cognitive impairments and autism traits in offspring. However, the underlying mechanisms remain unclear.
Enrique González-Madrid, Ma. Andreina Rangel-Ramírez, María C. Opazo, Sebastián A. Espinoza, Daniela Elgueta, Gonzalo I. Cancino, Elena Mery, Álvaro O. Ardiles, Luisa F. Duarte, Jorge A. Soto, Leandro J. Carreño, Felipe Simon, Susan M. Bueno, Pablo A. González, Alexis M. Kalergis, Claudia A. Riedel   +15 more
doaj   +1 more source

Current status of immunotherapy in acute myeloid leukemia

, 2021
Wenrui Li
openalex   +1 more source

Real-world outcomes versus clinical trial results of immunotherapy in stage IV non-small cell lung cancer (NSCLC) in the Netherlands [PDF]

, 2021
Christine M. Cramer‐van der Welle, Marjon V. Verschueren, Merel Tonn, Bas Peters, Franz M.N.H. Schramel, Olaf H. Klungel, Harry J.M. Groen, E.M.W. van de Garde, Elisabeth A. Kastelijn, L.C. Vermeer, B. E. E. M. van den Borne, J.W.G. van Putten, J. H. Schouwink, Annet Smit, A. A. J. Smit   +14 more
openalex   +1 more source

The importance of early immunotherapy in patients with faciobrachial dystonic seizures. [PDF]

, 2018
Faciobrachial dystonic seizures and limbic encephalitis closely associate with antibodies to leucine-rich glioma-inactivated 1 (LGI1). Here, we describe 103 consecutive patients with faciobrachial dystonic seizures and LGI1 antibodies to understand ...
Bi, Mian, Bien, Christian, Chu, Kon, Farooque, Pue, Gelfand, Jeffrey, Geschwind, Michael, Hirsch, Lawrence, Irani, Sarosh, Lang, Bethan, Leite, Maria, Makuch, Mateusz, Murchison, Andrew, Somerville, Ernest, Thompson, Julia, Vincent, Angela, Waters, Patrick   +15 more
core  

NEAT1_1 confers gefitinib resistance in lung adenocarcinoma through promoting AKR1C1-mediated ferroptosis defence

Cell Death Discovery
Gefitinib is one of the most extensively utilized epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) for treating advanced lung adenocarcinoma (LUAD) patients harboring EGFR mutation.
Shuman Zhen, Yunlong Jia, Yan Zhao, Jiali Wang, Boyang Zheng, Tianxu Liu, Yuqing Duan, Wei Lv, Jiaqi Wang, Fan Xu, Yueping Liu, Yi Zhang, Lihua Liu   +12 more
doaj   +1 more source

NT-I7, a novel long-acting interleukin-7, promotes anti-PD-1 efficacy in an autologous humanized melanoma model

Scientific Reports
Despite recent advancements in immunotherapy, most cancer patients still struggle to achieve sustained benefits, highlighting the need for new treatment strategies.
Yee Peng Phoon, Alexandra A. Wolfarth, Pauline Funchain, Jennifer S. Ko, Donghoon Choi, Eliska Dedkova, Daniela Duarte Bateman, Jessica Corvin, Jan J. Melenhorst, Brian R. Gastman   +9 more
doaj   +1 more source

TMOD-10. REPLICATION REPAIR DEFICIENT MOUSE MODELS PROVIDE INSIGHT ON HYPERMUTANT BRAIN TUMOURS AND COMBINATIONAL IMMUNOTHERAPY [PDF]

, 2019
Melissa A. Galati, Taylor Bridge, Sumedha Sudhaman, Dana Elshaer, Ayse B. Ercan, Lazar Joksimovic, Miki S. Gams, Karl P. Hodel, Tatiana Lipman, Iram Siddiqui, Richard de Borja, Victoria J. Forster, Alberto Martín, Éric Bouffet, Adam Shlien, Cynthia J. Guidos, Zachary F. Pursell, Cynthia Hawkins, Uri Tabori   +18 more
openalex   +1 more source