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Clustering of quantitative CT features identifies HCC subtypes with distinct prognosis and immune signatures. [PDF]
Eur Radiol ExpWu S +6 more
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Allergy and Asthma Proceedings, 2022
There are currently no biomarkers that can accurately predict clinical outcomes and segregate responders from nonresponders in allergen immunotherapy (AIT). Therefore, identifying a reliable predictive biomarker is essential to enable clinicians to tailor personalized therapy.
Tiak Ju, Tan +2 more
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There are currently no biomarkers that can accurately predict clinical outcomes and segregate responders from nonresponders in allergen immunotherapy (AIT). Therefore, identifying a reliable predictive biomarker is essential to enable clinicians to tailor personalized therapy.
Tiak Ju, Tan +2 more
openaire +2 more sources
Immunotherapy, 2021
Over the past two decades, significant progress has been achieved in the treatment of psoriasis by targeting the human cytokine network. At present, 11 biologicals - antibodies, and a soluble receptor - are used to neutralize key inflammatory cytokines.
Lilla Landeck +6 more
openaire +2 more sources
Over the past two decades, significant progress has been achieved in the treatment of psoriasis by targeting the human cytokine network. At present, 11 biologicals - antibodies, and a soluble receptor - are used to neutralize key inflammatory cytokines.
Lilla Landeck +6 more
openaire +2 more sources
Immunotherapy in cholangiocarcinoma
Current Opinion in Gastroenterology, 2021Purpose of review Cholangiocarcinoma is an aggressive heterogeneous group of cancers of the biliary epithelium and most patients are detected with advanced metastatic disease with poor prognosis. The therapeutic options are limited, and the current standard care as systemic therapy is still cytotoxic chemotherapy.
Raed, Al-Rajabi, Weijing, Sun
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Thoracic Surgery Clinics, 2020
Immune checkpoint inhibitor (ICI) therapy has been approved for several solid tumors, including non-small cell lung cancer. ICIs have shown unprecedented durable responses and higher response rates than chemotherapy in selected patients. The development of biomarkers that serve as predictors of response is crucial for treatment selection.
Jean G, Bustamante-Alvarez +1 more
openaire +2 more sources
Immune checkpoint inhibitor (ICI) therapy has been approved for several solid tumors, including non-small cell lung cancer. ICIs have shown unprecedented durable responses and higher response rates than chemotherapy in selected patients. The development of biomarkers that serve as predictors of response is crucial for treatment selection.
Jean G, Bustamante-Alvarez +1 more
openaire +2 more sources
Seminars in Respiratory and Critical Care Medicine, 2022
AbstractAsthma represents one of the biggest global health concerns with increasing prevalence and influence on global health. Several distinct asthma phenotypes have been identified with one of the most common, earliest recognized, and described being the allergic asthma phenotype, in which allergens trigger asthma through mechanisms involving ...
Jelena, Eremija, Tara F, Carr
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AbstractAsthma represents one of the biggest global health concerns with increasing prevalence and influence on global health. Several distinct asthma phenotypes have been identified with one of the most common, earliest recognized, and described being the allergic asthma phenotype, in which allergens trigger asthma through mechanisms involving ...
Jelena, Eremija, Tara F, Carr
openaire +2 more sources
Current Opinion in Otolaryngology & Head & Neck Surgery, 2010
The present article summarizes the 2008-2009 literature on allergen standardization and immunotherapy for inhalant and food sensitivities, with emphasis on delineation of the underlying immunologic changes and on evidence-based conclusions from such and clinical data.The efficacy of subcutaneous immunotherapy for inhalant allergies has been established
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The present article summarizes the 2008-2009 literature on allergen standardization and immunotherapy for inhalant and food sensitivities, with emphasis on delineation of the underlying immunologic changes and on evidence-based conclusions from such and clinical data.The efficacy of subcutaneous immunotherapy for inhalant allergies has been established
openaire +2 more sources