Results 111 to 120 of about 15,680 (203)

IMP dehydrogenase-2 drives aberrant nucleolar activity and promotes tumorigenesis in glioblastoma. [PDF]

Nat Cell Biol, 2019
Kofuji S, Hirayama A, Eberhardt AO, Kawaguchi R, Sugiura Y, Sampetrean O, Ikeda Y, Warren M, Sakamoto N, Kitahara S, Yoshino H, Yamashita D, Sumita K, Wolfe K, Lange L, Ikeda S, Shimada H, Minami N, Malhotra A, Morioka S, Ban Y, Asano M, Flanary VL, Ramkissoon A, Chow LML, Kiyokawa J, Mashimo T, Lucey G, Mareninov S, Ozawa T, Onishi N, Okumura K, Terakawa J, Daikoku T, Wise-Draper T, Majd N, Kofuji K, Sasaki M, Mori M, Kanemura Y, Smith EP, Anastasiou D, Wakimoto H, Holland EC, Yong WH, Horbinski C, Nakano I, DeBerardinis RJ, Bachoo RM, Mischel PS, Yasui W, Suematsu M, Saya H, Soga T, Grummt I, Bierhoff H, Sasaki AT.   +56 more
europepmc   +1 more source

Benzoxazoles, Phthalazinones, and Arylurea-Based Compounds with IMP Dehydrogenase-Independent Antibacterial Activity against Francisella tularensis. [PDF]

Antimicrob Agents Chemother, 2017
Gorla SK, Zhang Y, Rabideau MM, Qin A, Chacko S, House AL, Johnson CR, Mandapati K, Bernstein HM, McKenney ES, Boshoff H, Zhang M, Glomski IJ, Goldberg JB, Cuny GD, Mann BJ, Hedstrom L.   +16 more
europepmc   +1 more source

Inhibition of Calcineurin or IMP Dehydrogenase Exerts Moderate to Potent Antiviral Activity against Norovirus Replication. [PDF]

Antimicrob Agents Chemother, 2017
Dang W, Yin Y, Wang Y, Wang W, Su J, Sprengers D, van der Laan LJW, Felczak K, Pankiewicz KW, Chang KO, Koopmans MPG, Metselaar HJ, Peppelenbosch MP, Pan Q.   +13 more
europepmc   +1 more source

Structure of Cryptosporidium IMP dehydrogenase bound to an inhibitor with in vivo antiparasitic activity. [PDF]

Acta Crystallogr F Struct Biol Commun, 2015
Kim Y, Makowska-Grzyska M, Gorla SK, Gollapalli DR, Cuny GD, Joachimiak A, Hedstrom L.   +6 more
europepmc   +1 more source

Validation of IMP dehydrogenase inhibitors in a mouse model of cryptosporidiosis. [PDF]

Antimicrob Agents Chemother, 2014
Gorla SK, McNair NN, Yang G, Gao S, Hu M, Jala VR, Haribabu B, Striepen B, Cuny GD, Mead JR, Hedstrom L.   +10 more
europepmc   +1 more source

Role of the Mobile Active Site Flap in IMP Dehydrogenase Inhibitor Binding. [PDF]

ACS Infect Dis
Wang X, Rosenberg MM, Kim Y, Maltseva N, Cuny GD, Joachimiak A, Kuzmič P, Hedstrom L.   +7 more
europepmc   +1 more source

Hypoxia modulates the purine salvage pathway and decreases red blood cell and supernatant levels of hypoxanthine during refrigerated storage [PDF]

, 2018
Doctor, Allan, et al.,, Rogers, Stephen C   +2 more
core   +1 more source

Rapid sensitive and reproducible assays for human parathyrin [PDF]

, 1978
Kuflicki, G., Marschner, I., Scriba, Peter Christian, Wood, W. G.   +3 more
core   +1 more source

IMP metabolic mechanisms and IMPDH targeting strategies in tumor metabolic reprogramming and therapy (Review). [PDF]

Int J Mol Med
Zhu H, Wang H, Li X, Zhang W, Wang Y, Tan Q, Ying D, Shi Z, Song J.   +8 more
europepmc   +1 more source

Exploring <i>T. cruzi</i> IMPDH as a promising target through Chagas Box screening and AVN-944 inhibition. [PDF]

Antimicrob Agents Chemother
Lobo-Rojas A, Marchese L, Eufrasio AG, Souza GTD, Catelli MF, Faria JDN, Cordeiro AT.   +6 more
europepmc   +1 more source