Results 41 to 50 of about 15,680 (203)

Integrative analysis of circadian transcriptome and metabolic network reveals the role of de novo purine synthesis in circadian control of cell cycle.

open access: yesPLoS Computational Biology, 2015
Metabolism is the major output of the circadian clock in many organisms. We developed a computational method to integrate both circadian gene expression and metabolic network.
Ying Li   +5 more
doaj   +1 more source

Genes related to osmoregulation and antioxidation play important roles in the response of Trollius chinensis seedlings to saline-alkali stress

open access: yesFrontiers in Plant Science, 2023
Saline-alkali stress is one of the main abiotic stress factors affecting plant growth and development. Trollius chinensis is a perennial herbal medicinal plant with high values for garden application.
Rongmiao Hou   +6 more
doaj   +1 more source

Molecular regulators of glucose and lipid metabolism in skeletal muscle [PDF]

open access: yes, 2012
Skeletal muscle is a primary site of insulin action and insulin-stimulated glucose transport and occupies a center stage in maintaining whole body glucose and lipid homeostasis.
Kulkarni, Sameer S
core   +1 more source

Historical Perspectives in the Development of Antiviral Agents Against Poxviruses

open access: yesViruses, 2010
The poxvirus vaccinia virus (VV) served as the model virus for which the first antivirals, the thiosemicarbazones, were identified. This dates back to 1950; and, although there is at present no single antiviral drug specifically licensed for the ...
Erik De Clercq
doaj   +1 more source

Proteomes of Lactobacillus delbrueckii subsp. bulgaricus LBB.B5 Incubated in Milk at Optimal and Low Temperatures. [PDF]

open access: yes, 2017
We identified the proteins synthesized by Lactobacillus delbrueckii subsp. bulgaricus strain LBB.B5 in laboratory culture medium (MRS) at 37°C and milk at 37 and 4°C.
Angel Angelov   +6 more
core   +2 more sources

Metabolic engineering of Pichia pastoris for myo-inositol production by dynamic regulation of central metabolism

open access: yesMicrobial Cell Factories, 2022
Background The methylotrophic budding yeast Pichia pastoris GS115 is a powerful expression system and hundreds of heterologous proteins have been successfully expressed in this strain. Recently, P.
Qiquan Zhang   +11 more
doaj   +1 more source

Comparative proteomic profiling reveals molecular characteristics associated with oogenesis and oocyte maturation during ovarian development of Bactrocera dorsalis (Hendel) [PDF]

open access: yes, 2017
Time-dependent expression of proteins in ovary is important to understand oogenesis in insects. Here, we profiled the proteomes of developing ovaries from Bactrocera dorsalis (Hendel) to obtain information about ovarian development with particular ...
Wei, Dong   +6 more
core   +1 more source

Effects of Transport Time on Stress Level and Meat Quality in Yangzhou Goose(运输时间对扬州鹅应激程度和肉品质的影响) [PDF]

open access: yesShipin kexue jishu xuebao, 2018
This study evaluated the effects of transport time on stress level and meat quality of Yangzhou goose. Thirty Yangzhou geese were randomly assigned into five treatments with each group having six geese.
ZHANG Shuxiang(张舒翔)   +4 more
doaj   +1 more source

Analysis of cellular responses of macrophages to zinc ions and zinc oxide nanoparticles: a combined targeted and proteomic approach [PDF]

open access: yes, 2014
Two different zinc oxide nanoparticles, as well as zinc ions, are used to study the cellular responses of the RAW 264 macrophage cell line. A proteomic screen is used to provide a wide view of the molecular effects of zinc, and the most prominent results
Armand, Lucie   +13 more
core   +4 more sources

Artesunate Ameliorates APAP‐induced Liver Injury by Promoting NEDD4L‐Mediated Ubiquitination and Degradation of TXNIP

open access: yesAdvanced Science, EarlyView.
ABSTRACT Liver injury can lead to severe acute liver failure and even death in patients. Artesunate (ART), which is a derivative of artemisinin that has been approved by the FDA for the treatment of malaria, has significant regulatory effects on cell death and inflammation.
Zhe Zhang   +17 more
wiley   +1 more source

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