Results 111 to 120 of about 13,192,083 (308)

Investments in irrigation projects - an impact analysis [PDF]

open access: yes
Physical infrastructure development is a powerful means of promoting economic growth as (i) it creates production facilities, “crowds in†private investment and thereby stimulates economic activities, (ii) reduces transaction and marketing costs ...
Kumbhare, S.L., Sen, Madhurima
core   +1 more source

Representation of the German transmission grid for Renewable Energy Sources impact analysis

open access: yes, 2016
The increasing impact of fossil energy generation on the Earth ecological balance is pointing to the need of a transition in power generation technology towards the more clean and sustainable Renewable Energy Sources (RES).
Mureddu, Mario
core   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Analysis of the Impact and Value of Community Benefit Clauses in Procurement [PDF]

open access: yes, 2015
This research draws on data from a large scale e-survey of public organisations and in-depth analysis of 24 individual ...
Glass, Andrea   +3 more
core  

Impact Analysis of Baseband Quantizer on Coding Efficiency for HDR Video

open access: yes, 2016
Digitally acquired high dynamic range (HDR) video baseband signal can take 10 to 12 bits per color channel. It is economically important to be able to reuse the legacy 8 or 10-bit video codecs to efficiently compress the HDR video.
Su, Guan-Ming, Wong, Chau-Wai, Wu, Min
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Impact Analysis of Multispecies Marine Resource Management [PDF]

open access: yes
In an attempt to study the regional income and employment impact of different harvesting regimes and harvesting patterns of marine resources, this article demonstrates an approach of combining multispecies bioeconomic modeling and input-output (1-0 ...
Heen, Knut
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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