Results 121 to 130 of about 65,026,818 (351)

Extreme weather events in early summer 2018 connected by a recurrent hemispheric wave-7 pattern

Environmental Research Letters, 2019
The summer of 2018 witnessed a number of extreme weather events such as heatwaves in North America, Western Europe and the Caspian Sea region, and rainfall extremes in South-East Europe and Japan that occurred near-simultaneously.
Kai Kornhuber, Scott Osprey, Dim Coumou, Stefan Petri, Vladimir Petoukhov, Stefan Rahmstorf, Lesley Gray   +6 more
doaj   +1 more source

Change impact analysis of enterprise architectures

IRI -2005 IEEE International Conference on Information Reuse and Integration, Conf, 2005., 2005
An enterprise architecture is a high-level description intended to capture the vision of an enterprise integrating all its dimensions: organization structure, business processes, and infrastructure. Every single part of an enterprise is subject to change, and each change may have significant consequences within all domains of the enterprise.
F.S. de Boer (Frank), M.M. Bonsangue (Marcello), L.P.J. Groenewegen (Luuk), A. Stam, S. Stevens, L.W.N. van der Torre (Leon)   +5 more
openaire   +3 more sources

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Impact Strategy Development: Workshops to Co-create your Strategy

This tool serves as a guide for conducting workshops that enable strategic planning within your school. These workshops provide a structured environment for refection and dialogue, which empowers participants to articulate their aspirations for societal ...
Evaluating Societal Impact
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Flows of Knowledge: A Method for Impact Assessment

The Flows of Knowledge evaluation method, as introduced by Meagher, Lyall and Nutley (2008) and described in Edwards and Meagher (2020), provides a framework for assessing the impacts of scientific research on policy and practice.
Evaluating Societal Impact
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Preparing case studies for impact within SEP (2021-2027)

Every six years, on a rolling basis, Dutch universities and research institutes are evaluated according to the Strategy Evaluation Protocol (SEP).Based on the experiences with the Strategy Evaluation Protocol (SEP) at the Erasmus University Rotterdam as ...
Evaluating Societal Impact
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source