Results 41 to 50 of about 389,827 (297)
Daemons and DAMA: Their Celestial-Mechanics Interrelations [PDF]
, 2007 The assumption of the capture by the Solar System of the electrically charged Planckian DM objects (daemons) from the galactic disk is confirmed not only by the St.Petersburg (SPb) experiments detecting particles with ...
Allen C. W. +8 more
core +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Materials Research Express, 2021 In this paper, a general three-dimensional finite element model composed of eight-node three-dimension cohesive elements and eight-node solid elements with reduced integration for low-velocity impact analysis of composite materials is established ...
J R Shao, N Liu, Z J Zheng
doaj +1 more source
Stabilized material point methods for coupled large deformation and fluid flow in porous materials
, 2019 The material point method (MPM) has been increasingly used for the simulation of large deformation processes in fluid-infiltrated porous materials. For undrained poromechanical problems, however, standard MPMs are numerically unstable because they use ...
Choo, Jinhyun, Zhao, Yidong
core +2 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Nature CommunicationsSolid-state Li-ion batteries, based on Ni-rich oxide cathodes and Li-metal anodes, can theoretically reach a high specific energy of 393 Wh kg−1 and hold promise for electrochemical storage.
Chuanlai Liu, Franz Roters, Dierk Raabe
doaj +1 more source
RUDN Journal of Ecology and Life Safety, 2023 The possibilities of increasing the ecological and technological efficiency of the innovative coal-watercoal cluster of housing and communal services, including the mechanics of coal destruction in a hydraulic shock installation, are considered.
Tatyana V. Zommer +2 more
doaj +1 more source
Compressible Air Entrapment in High-Speed Drop Impacts on Solid Surfaces
, 2012 Using high-speed photography coupled with optical interference, we experimentally study the air entrapment during a liquid drop impacting a solid substrate.
Liu, Yuan, Tan, Peng, Xu, Lei
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Linear and non-linear dynamic analyses of sandwich panels with face sheet-tocore debonding [PDF]
, 2020 А survey of recent developments in the dynamic analysis of sandwich panels with face sheet-to-core debonding is presented. The finite element method within the ABAQUSTM code is utilized.
Burlayenko, V. N., Sadowski, Tomasz
core