Results 41 to 50 of about 392,524 (314)

Strain Prediction of Grain in Solid Rocket Motor under the Pressure Curing Molding Technology

International Journal of Aerospace Engineering, 2023
The residual strain generated in grains during the propellant manufacturing process can significantly impact the safety and stability of solid rocket motors.
Kaining Zhang, Chunguang Wang, Qun Li, Zhenyu Guo   +3 more
doaj   +1 more source

Security and defence of mobile systems under impact [PDF]

, 2008
The Group “Dynamics and Fracture of Structural Elements” offers its experience in Solid Mechanics analysis for the study of the impact protection of vehicles, aircrafts and persons.
Arias Hernández, Ángel, Zaera Polo, Ramón Eulalio   +1 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Research progress on typical mechanical problems of thermoplastic composites

Journal of Aeronautical Materials, 2022
Thermoplastic composites have excellent mechanical properties and are ideal structure materials for reusable launch vehicles. The research of mechanical behavior has attracted tremendous attention in the fields of solid mechanics and material sciences ...
LIU Mingwei, GAO Yihang, ZHANG Dapeng, DUAN Jingbo, LEI Yongjun   +4 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Numerical comparison between Hashin and Chang-Chang failure criteria in terms of inter-laminar damage behavior of laminated composite

Materials Research Express, 2021
In this paper, a general three-dimensional finite element model composed of eight-node three-dimension cohesive elements and eight-node solid elements with reduced integration for low-velocity impact analysis of composite materials is established ...
J R Shao, N Liu, Z J Zheng
doaj   +1 more source

Measurements of Solid Spheres Bouncing Off Flat Plates [PDF]

, 1990
Recent years have seen a substantial increase of interest in the flows of granular materials whose rheology is dominated by the physical contact between particles and between particles and the containing walls.
Brennen, C. E., Chaney, K., Sondergaard, R.   +2 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Role of grain-level chemo-mechanics in composite cathode degradation of solid-state lithium batteries

Nature Communications
Solid-state Li-ion batteries, based on Ni-rich oxide cathodes and Li-metal anodes, can theoretically reach a high specific energy of 393 Wh kg−1 and hold promise for electrochemical storage.
Chuanlai Liu, Franz Roters, Dierk Raabe
doaj   +1 more source

Wetting, roughness and hydrodynamic slip [PDF]

, 2011
The hydrodynamic slippage at a solid-liquid interface is currently at the center of our understanding of fluid mechanics. For hundreds of years this science has relied upon no-slip boundary conditions at the solid-liquid interface that has been applied ...
Belyaev, Aleksey V., Vinogradova, Olga I.   +1 more
core