Results 71 to 80 of about 10,613,174 (259)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
High pressure-induced structural effects in plastic packaging
, 2022 S.555-566Today, flexible vacuum packages are predominantly used for products to be subjected to high pressure treatment. However, tray packages with a modified atmosphere are in demand, which provide a high failure rate with respect to gas and water ...
Richter, T. +3 more
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AgricultureGrain breakage serves as a primary causative factor for microbial infestation and oxidative deterioration, significantly diminishing product value and resulting in substantial grain waste and economic losses.
Yawen Xiao +6 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Impact Strategy Development Toolkit
This tool outlines the process and useful tools for developing school-level impact strategies. It guides you through the strategy development journey, from the initial preparatory activities to the evaluation.
Evaluating Societal Impact
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Applied SciencesDeep learning algorithms are pivotal in the identification and classification of microseismic signals in mines subjected to impact pressure. However, conventional machine learning techniques often struggle to balance interpretability, computational ...
Jizhi Zhang, Hongwei Wang, Tianwei Shi
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Productive Interactions (SIAMPI): A Method for Impact Assessment
This resource informs readers about the SIAMPI framework for impact assessment introduced by Spaapen and Van Drooge (2011), enriched with the experiences of the Evaluating Societal Impact team at EUR using the method in two case studies.
Evaluating Societal Impact
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High Pressure Hugoniot Measurements in Solids Using Mach Reflections [PDF]
, 2011 Shock compression experiments provide access to high pressures in a laboratory setting. Matter at extreme pressures is often studied by utilizing a well controlled planar impact between two flat plates to generate a one dimensional shock wave.
Brown, Justin Lee
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Scaling Behavior of Sloshing Impact Pressures Based on Event Distribution and Regime Classification
Journal of Marine Science and EngineeringSloshing in partially filled tanks generates significant impact pressures that threaten the structural integrity of LNG cargo containment systems, and accurate scaling of these impacts remains a critical issue.
Hyung-Min Baek +9 more
doaj +1 more source