Results 91 to 100 of about 10,613,174 (259)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Impact Indicators: Overview and Menu Selection

open access: yes
The tool Impact indicators - overview and selection menu was designed by the Evaluating Societal Impact (ESI) strategic project at Erasmus University Rotterdam for academics and research units who want to indicate how their academic work relates to ...
Evaluating Societal Impact
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Impact Strategy Development: Questions Bank and Interview Guide

open access: yes
The tool ‘Impact Strategy Development: Questions Bank and Interview Guide’ consists of (1) a three step interview guide and (2) an Excel file with a questions bank to use and tailor for your interviews or other methods for engaging with your community ...
Evaluating Societal Impact
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Thinking About my Impact and Engagement: A Worksheet

open access: yes
What does making positive societal impact mean to you? How do you map current and potential partners and beneficiaries? How to align your work to their needs? This workshop package offers a brief printable worksheet with accompanying presentation slides,
Evaluating Societal Impact
core   +1 more source

The impact of nurses’ values on the prevention of pressure ulcers: a Straussian grounded theory study [PDF]

open access: yes, 2012
This is a Straussian grounded theory study about the impact of nurses’ values on pressure ulcer prevention. Semi-structured interviews were used to gather data from participants (n=16) who were recruited from the non-acute adult medical wards of 14 ...
Samuriwo, Raymond K.
core  

The impact of sleep pressure, circadian phase and an ADA-polymorphism on working memory: a behavioral, electrophysiological, neuroimaging approach [PDF]

open access: yes, 2015
The need for sleep, the so-called sleep pressure, increases continuously during wakefulness and decreases during sleep again, in particular during intense deep sleep (Borbely, 1982).
Reichert, Carolin Franziska
core   +1 more source

An Executive Summary of the Economic Impact of Grand Beach in Galveston, Texas

open access: yes, 2013
This report presents the results of an economic impact analysis performed by Impact DataSource, Austin, Texas. The analysis was to determine the impact that Grand Beach residential and hotel development in Galveston, Texas will have on the economy of the
Impact DataSource, Walker, Jerry
core   +2 more sources

Evaluation of Water Impact For Symmetric Wedge by Experimental and Numerical Methods

open access: yesInternational Journal of Applied Mechanics and Engineering, 2019
Evaluation of impact loads when a ship hull contacts the wave surface is one of the main issues for researchers who are going to design the structure of marine vehicles.
M. Nikfarjam   +4 more
doaj   +1 more source

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