Results 81 to 90 of about 10,613,174 (259)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Building Impact Stories: An Inspirational Guide for Communicators

open access: yes
This guide is designed to assist (external) communication professionals in articulating the societal impact of university activities, projects and initiatives stemming from the university’s education, research and engagement core missions and the ...
Evaluating Societal Impact
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Evaluating Student Impact Capacity: A Guidebook for Teachers

open access: yes
This guidebook is designed to assist course coordinators in evaluating students’ impact capacity in their courses. It contains the definition of students’ impact capacity and a non-exhaustive list of example questions for evaluating societal impact ...
Evaluating Societal Impact
core   +1 more source

Evaluation of the impact of atmospheric pressure in different seasons on blood pressure in patients with arterial hypertension [PDF]

open access: yes, 2016
Objectives: Atmospheric pressure is the most objective weather factor because regardless of if outdoors or indoors it affects all objects in the same way.
Kurpesa, Małgorzata   +23 more
core   +2 more sources

Damage on a Solid–Liquid Interface Induced by the Dynamical Behavior of Injected Gas Bubbles in Flowing Mercury

open access: yesFluids
Microbubbles have been applied in various fields. In the mercury targets of spallation neutron sources, where cavitation damage is a crucial issue for life estimation, microbubbles are injected into the mercury to absorb the thermal expansion of the ...
Hiroyuki Kogawa   +2 more
doaj   +1 more source

Review on the impacts of external pressure on sonochemistry

open access: yesUltrasonics Sonochemistry
The impact of hydrostatic pressure, commonly known as ambient or external pressure, on the phenomenon of sonochemistry and/or sonoluminescence has been extensively investigated through a multitude of experimental and computational studies, all of which have emphasized the crucial role played by this particular parameter.
Slimane Merouani   +4 more
openaire   +4 more sources

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Proximity Lens on Structural Collaborations: A Method for Impact Assessment

open access: yes
This resource provides a description of ‘proximities’ in impact assessment, building on Boschma (2005) and Knoben & Oerlemans (2006). Proximity dimensions provide a lens to identify and highlight the conditions that enable successful cooperation and ...
Evaluating Societal Impact
core   +1 more source

Pressure-Enhanced Liquid Chromatography, a Proof of Concept: Tuning Selectivity with Pressure Changes and Gradients

open access: yes, 2022
Many chromatographers have observed that the operating pressure can dramatically change the chromatographic retention of solutes. Small molecules show observables changes, yet even more sizable effects are encountered with large biomolecules.
Michael Fogwill (4175272)   +2 more
core   +1 more source

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