Results 71 to 80 of about 1,148,207 (317)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Investigation on low-velocity impact response and energy absorptionof enhanced X-shaped lattice mechanical metamaterials

open access: yesBaozha yu Chongji
Lattice mechanical metamaterials have been widely used in various fields due to the lightweight, flexible designability and excellent impact resistance.
Chang LU   +10 more
doaj   +1 more source

Maximal strength training: the impact of eccentric overload [PDF]

open access: yesJournal of Neurophysiology, 2018
The search for the most potent strength training intervention is continuous. Maximal strength training (MST) yields large improvements in force-generating capacity (FGC), largely attributed to efferent neural drive enhancement. However, it remains elusive whether eccentric overload, before the concentric phase, may augment training-induced ...
Tøien, Tiril   +4 more
openaire   +3 more sources

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Experimental and crystal plasticity finite element study of dynamic shear behavior of CoCrNiSi0.3 medium-entropy alloy

open access: yesJournal of Materials Research and Technology
Single-phase CrCoNi-based medium-entropy alloys (MEAs) have garnered considerable attention as a promising class of metallic materials. However, despite this growing interest, the dynamic mechanical response of CrCoNi-based MEAs at high strain rate ...
Huiqing Fang   +9 more
doaj   +1 more source

Impact strength for notched high strength steel.

open access: yesJournal of the Society of Materials Science, Japan, 1985
An instrumented impact charpy test was carried out to evaluate the effects of the notch shape, hardness, and carburized depth on the impact bending strength of notched high strength steels (SCM 440 and SCM 415 steels).The principal results were as follows:(1) The impact bending strength of the notched high strength steel was in near proportion to the ...
KUMASAWA, Michio   +3 more
openaire   +2 more sources

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Fine regulation of sigma phase achieves excellent mechanical properties in Co-free CrFeNiSi0.2 medium entropy alloy

open access: yesJournal of Materials Research and Technology
The balance between strength and plasticity is the ultimate objective in the exploration of alloy design. This study focuses on achieving synergy between strength and toughness in the CrFeNiSi0.2 medium entropy alloy through various heat treatments to ...
T.X. Bai   +9 more
doaj   +1 more source

Impact strength of Epoxy composites with fly ashe as the fillers

open access: yes, 2018
Samples of epoxy composites containing three types of fly ash were prepared. The used epoxy resin system was low molecular weight unmodified epoxy resin based on bisphenol A, certified EPD for significant CO2 savings in production, low oil content and ...
Novotná Jana   +2 more
core  

Impact of Vibration Time on Compressive Strength of Hardened Sandcrete Building Blocks [PDF]

open access: yes, 2012
The majority of the sandcrete blocks used in the Nigerian building industry fall short of the minimum specification standards. There is evidence to suggest a wide variation in compressive strength from one block manufacturer to another and also within ...
Alohan Omoregie, Omoregie, Alohan
core   +1 more source

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