Results 91 to 100 of about 1,148,207 (317)

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Temperature-dependent mechanical behavior in a novel hierarchical B2-strengthened high entropy alloy: Microscopic deformation mechanism and yield strength prediction

Materials & Design
Integration of twinning and hierarchical microstructure into a face-centered cubic (FCC) matrix is a novel research approach for advancing high-temperature alloys, enhancing strength without the need for costly heavy elements.
Tuanwei Zhang, Renlong Xiong, Hui Chang, Jinxiong Hou, Dan Zhao, Zhong Wang, Zhouzhu Mao, Tianxiang Bai, Zhiming Jiao, Jianjun Wang, Zhihua Wang   +10 more
doaj   +1 more source

Recovery of muscle strength and power after limb-lengthening surgery

, 2010
Barker KL, Lamb SE, Simpson HRW. Recovery or muscle strength and power after limb-lengthening surgery. Arch Phys Med Rehabil 2010;91:384-8. Objective: To report muscle strength, power, and function after limb-lengthening surgery performed by using ...
Lamb, Sarah, Barker, Karen L, Simpson, HR, Lamb, S. E. (Sallie E.), Simpson, Hamish R. W., Barker, Karen, MSc, Barker, KL, Simpson, Hamish R W, Lamb, Sallie E, Barker, Karen, Lamb, SE   +10 more
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Strong yet ductile eutectic high-entropy FCC/Laves composite fabricated by powder plasma arc additive manufacturing: Mechanical property, microstructure evolution, and constitutive description over a wide range of temperatures and strain rates

Journal of Materials Research and Technology
To enhance the strength and toughness of metallic materials simultaneously over a wide range of temperatures and strain rates, a eutectic high-entropy FCC/Laves composite with a heterogeneous initial microstructure was fabricated by powder plasma arc ...
Hongxu Guo, Jianjun Wang, Xiangxiang Tu, Xizhang Chen, Shengguo Ma, Dan Zhao, Zhiming Jiao, Tuanwei Zhang, Ruifeng Wang, Zhihua Wang   +9 more
doaj   +1 more source

Improved impact performance of marine sandwich panels using through-thickness reinforcement: Experimental results [PDF]

, 2010
This paper presents results from a test developed to simulate the water impact (slamming) loading of sandwich boat structures. A weighted elastomer ball is dropped from increasing heights onto rigidly supported panels until damage is detected. Results
Davies, Peter, Partridge, I.K, Cartie, D. D. R., Partridge, I. K., Cartié, D., Baral, N., Davies, P., Cartié, Denis D. R., Partridge, Ivana K., Baley, C.   +9 more
core   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

The influence of fibre length and concentration on the properties of glass fibre reinforced polypropylene : 7. interface strength and fibre strain in injection moulded long fibre PP at high fibre content

, 2007
The mechanical performance of injection moulded long glass fibre reinforced polypropylene with a glass fibre content in the range 0-73% by weight has been investigated.
Thomason, J.L.
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source