Results 121 to 130 of about 25,604,119 (393)
Purification tags markedly affect self‐aggregation of CPEB3
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito+6 more
wiley +1 more source
Nonlinear seismic analysis of a reactor structure impact between core components [PDF]
The seismic analysis of the FFTF-PIOTA (Fast Flux Test Facility-Postirradiation Open Test Assembly), subjected to a horizontal DBE (Design Base Earthquake) is presented. The PIOTA is the first in a set of open test assemblies to be designed for the FFTF.
Hill, R. G.
core +1 more source
Circulating histones as clinical biomarkers in critically ill conditions
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez+17 more
wiley +1 more source
Analyzing crash worthiness of the automotive parts has been posing a great challenge in the sheet metal and automotive industry since several decades.
Chandran, Sarath, Verleysen, Patricia
core
Impact of grain evolution on the chemical structure of protoplanetary disks
We study the impact of dust evolution in a protoplanetary disk around a T Tauri star on the disk chemical composition. For the first time we utilize a comprehensive model of dust evolution which includes growth, fragmentation and sedimentation.
A. I. Vasyunin+49 more
core +1 more source
Technological Development: Investment Structure Impact
The study is aimed at determining the impact of a technology investment structure on changes in technological effectiveness of the economy that should be taken into account in the medium and long term.
Sukharev Oleg S.
doaj +1 more source
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao+7 more
wiley +1 more source
The capital structure depends on many factors, of which the asset structure is considered to be a primary factor. In accordance with the golden balance rule, companies should harmonize the deadlines of binding assets and deadlines of obligations maturity
Јелена Пољашевић
doaj +3 more sources
The Nadir Crater offshore West Africa: A candidate Cretaceous-Paleogene impact structure. [PDF]
Nicholson U+3 more
europepmc +1 more source
Single‐cell insights into the role of T cells in B‐cell malignancies
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source