Results 141 to 150 of about 25,604,119 (393)
Analysis of simple 2-D and 3-D metal structures subjected to fragment impact [PDF]
Theoretical methods were developed for predicting the large-deflection elastic-plastic transient structural responses of metal containment or deflector (C/D) structures to cope with rotor burst fragment impact attack.
Rodal, J. J. A.+3 more
core +1 more source
Surface damage mitigation of titanium and its alloys via thermal oxidation: A brief review
Titanium (Ti) and its alloys have been extensively applied in various fields of chemical industry, marine, aerospace and biomedical devices because of a specific combination of properties such as high strength to weight ratio, exceptional corrosion ...
Lin Naiming+15 more
doaj +1 more source
Experimental Study on the Performance of Polyurethane-Steel Sandwich Structure under Debris Flow
Polyurethane-steel sandwich structure, which creatively uses the polyurethane-steel sandwich composite as a structural material, is proposed to strengthen the impact resistance of buildings under debris flow.
Peizhen Li, Shutong Liu, Zheng Lu
doaj +1 more source
Rewriting the dendritic cell code in cancer—from subset identity to immunotherapeutic design
Dendritic cells (DCs) play central roles in cancer immunity but are often subverted by the tumor microenvironment. This review explores the diversity of DC subsets, their functional plasticity, and emerging therapeutic strategies to reprogram DCs for enhanced antitumor responses, including vaccines, in vivo targeting, and DC‐based immunotherapies ...
Estevão Carlos Silva Barcelos+3 more
wiley +1 more source
New perspectives on the Popigai impact structure [PDF]
The record of large-scale cratering on Earth is scant, and the only currently 'proven' 100-km-class impact structure known to have formed within the Cenozoic is Popigai, located in the Siberian Arctic at 71.5 deg N, 111 deg E.
Deino, A. L., Garvin, J. B.
core +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan+2 more
wiley +1 more source
The impact of immigration on the wage structure : Spain 1995-2002 [PDF]
In this paper we estimate the impact of inward migration flows on the Spanish wage structure over the period 1995-2002 by constructing counterfactual wage distributions that provide the wages that would have been observed had individual and job ...
Carrasco, Raquel+2 more
core +1 more source
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli+10 more
wiley +1 more source
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin+14 more
wiley +1 more source
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak+14 more
wiley +1 more source