Results 41 to 50 of about 249,201 (263)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
New Experimental Technique for Dynamic Bending of Composite Materials
Engineering Transactions, 2014 The paper is reporting a new experimental technique to study the dynamic behaviour of composite materials subjected to bending direct impact. It is based on the Hopkinson bar system allowing to observe material behaviour at very high impact velocities ...
Abdellah MASSAQ +2 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Numerical analysis of geometrical and mechanical characteristics of the sliding mass influences on impulsive wave generation in dam reservoirs [PDF]
محیط زیست و مهندسی آبImpulsive waves caused by landslides into lakes and dam reservoirs strike the shores and dam bodies as large waves. The most important factor in their generation is the transfer of momentum from the mass to the water, which can cause damage.
Fateme Maleki +2 more
doaj +1 more source
A REVIEW OF PENETRATION TUNGSTEN BASED PROJECTILE ON DEPTH OF PENETRATION AT ARMOR OF CERAMIC BASED
Jurnal Pertahanan: Media Informasi tentang Kajian dan Strategi Pertahanan yang Mengedepankan Identity, Nasionalism & Integrity, 2020 Nowadays, tungsten-based material is used for the core of projectile, while ceramic-based is used for the main material of armor. Tungsten-based material is chosen because it has density and hardness superior to steel based-material.
Abdul Basyir +2 more
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Materials Research Express, 2023 Pneumatic shot peening is a widely used surface strengthening method. During the peening process, shots often collide with each other, resulting in large energy loss and small compressive residual stress.
Genshang Wu +6 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Constraining the Pulsar 3D Velocity Distribution: The Impact of Spin–Velocity Alignment
The Astrophysical JournalAbstract Quantifying the natal kick distribution of pulsars is essential for understanding supernova physics and binary evolution, yet measurements are historically limited by the lack of radial velocity data. Most previous studies rely on transverse velocities under the assumption of spatial isotropy.
Zheng Li +4 more
openaire +2 more sources