Results 51 to 60 of about 1,136,478 (300)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

A model for collisions in granular gases

, 1996
We propose a model for collisions between particles of a granular material and calculate the restitution coefficients for the normal and tangential motion as functions of the impact velocity from considerations of dissipative viscoelastic collisions ...
C. A. Coulomb, C. K. K. Lun, C. S. Campbell, D. C. Rapaport, F. Dinkelacker, F. G. Bridges, F. Spahn, Frank Spahn, G. Baumann, G. Peng, G. W. Baxter, G. W. Baxter, G. W. Baxter, G. W. Baxter, G. W. Baxter, H. Czichos, H. Hertz, H. J. Herrmann, H. J. Herrmann, H. M. Jaeger, H. Puhl, I. Goldhirsch, J. A. C. Gallas, J. A. Greenwood, J. M. Carlson, J. M. Carlson, J. P. Dilley, J. Wisdom, J.-M. Hertzsch, Jan-Martin Hertzsch, K. L. Johnson, K. L. Schick, L. D. Landau, Nikolai V. Brilliantov, O. R. Walton, P. A. Thompson, P. Bak, P. Cundall, P. Devillard, P. Evesque, P. Goldreich, P. K. Haff, R. Burridge, R. Greenberg, R. Jullien, S. Araki, S. F. Edwards, S. F. Edwards, S. F. Foerster, S. R. Nagel, T. G. Drake, T. G. Drake, T. G. Drake, T. Pöschel, T. Pöschel, T. Pöschl, Thorsten Pöschel, V. Buchholtz, W. Goldsmith, W. H. Press, W. M. Visscher, Y. H. Pao, Y. H. Taguchi, Y. Tsuji   +63 more
core   +2 more sources

Mechanoluminescence of nylon under high velocity impact

Journal of Physics: Conference Series, 2014
The light emissions produced during deformation of solids induced by any mechanical action is called mechanoluminescence (ML). This phenomenon was reported mostly in hypervelocity impacts. Using high speed video-recording, the authors found evidence of ML for nylon at much lower impact velocity (of the order of 100 m/s).
BONORA, Nicola, RUGGIERO, Andrew, IANNITTI, Gianluca, ABBATE, Carmine, IANNUZZO, Francesco, BUSATTO, Giovanni   +5 more
openaire   +3 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Microstructural Insights into Solid Particle Erosion in a High-Chromium Cast Iron

Metals
Solid particle erosion (SPE) significantly limits the service life of High-Chromium Cast Irons (HCCIs), widely used in power generation and mining industries.
Alessio Suman, Annalisa Fortini, Nicola Zanini   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Static and Dynamic Four-Point Flexural Tests of Concrete Beams with Variation in Concrete Quality, Reinforcement Properties and Impact Velocity

Nordic Concrete Research, 2021
This paper discusses the results from three experimental test series previously conducted. The tests consist of quasi-static monotonic and dynamic four-point flexural tests on reinforced concrete beams.
Peterson Viktor, Ansell Anders
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Impact Velocity and Coefficient of Restitution for a Tennis Ball Impacting a Tennis Racquet

International Scholastic Journal of Science, 2015
The impact and exit velocities of a tennis ball impacting on a fixed tennis racquet were measured with high speed video analysis to determine the coefficient of restitution (COR).
Mongkol Sukpraprut
doaj