Results 61 to 70 of about 249,201 (263)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Coefficient of Restitution of a Squash Ball

open access: yesInternational Scholastic Journal of Science, 2019
The coefficient of restitution of a Double Yellow Dot squash ball was examined at impact velocities ranging from 13 to 29 m/s. A high-speed camera was used with video analysis to record and analyze the motion of a squash ball as it collided against a ...
Marvin Limpijankit
doaj  

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Impact of Cavitation on Velocity Distribution

open access: yes, 2021
The flow inside rectangular shape nozzle is simulated in which the rectangular shape orifice was also considered with incline. CFD (Computational Fluid Dynamic) approach is used in this study along with finite volume scheme. The two-phase flow is considered homogenous and k-ε turbulent model is used to consider velocity and pressure fluctuations ...
Erik, Arthur, Arthur, Erik
openaire   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Mechanoluminescence of nylon under high velocity impact

open access: yesJournal of Physics: Conference Series, 2014
The light emissions produced during deformation of solids induced by any mechanical action is called mechanoluminescence (ML). This phenomenon was reported mostly in hypervelocity impacts. Using high speed video-recording, the authors found evidence of ML for nylon at much lower impact velocity (of the order of 100 m/s).
BONORA, Nicola   +5 more
openaire   +3 more sources

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

The Effect of Strain Rate on Bone Fragility and Clinical Applications

open access: yesBioengineering
The loading rate influences the fracture mechanics of bone. The effect of strain rate on bone tissue was studied. Two sets of dynamic tests were performed, where the impact energy E = 70 J was kept as a constant value.
Marijo Bekić   +4 more
doaj   +1 more source

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