Results 31 to 40 of about 364,049 (308)

Assessment of cardiovascular risk factors in persons with impaired glucose tolerance [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2019
Introduction/Objective. The aim of the study was to determine the profile of cardiovascular risk factors in patients with impaired glucose tolerance (IGT) in comparison to patients with impaired fasting glucose (IFG). Methods.
Novaković Tatjana, Mirković Zlatica, Milošević Nenad, Živković Zorica, Mirić Dijana, Mirković Jana, Perić Vladan, Milošević Jovana   +7 more
doaj   +1 more source

The prevalence of impaired fasting glucose and undiagnosed diabetes mellitus and associated risk factors among adults living in a rural Koladiba town, northwest Ethiopia

BMC Research Notes, 2017
Diabetes mellitus is becoming a big public health challenge, particularly in developing countries like Ethiopia. It is a manageable disease if early screening and follow up is made. However, as studies in Ethiopia are limited and unorganized, determining
Abebaw Worede, Shitaye Alemu, Y. Gelaw, Molla Abebe   +3 more
semanticscholar   +1 more source

Long term prognostic implication of newly detected abnormal glucose tolerance among patients with stable cardiovascular disease: a population-based cohort study

Journal of Translational Medicine, 2021
Background Fasting plasma glucose (FPG) and 2-h post challenge plasma glucose (2 h-PCPG), whether as continuous or categorical variables, are associated with incident cardiovascular disease (CVD) and diabetes; however, their role among patients with ...
Maryam Kabootari, Samaneh Asgari, Seyedeh Maryam Ghavam, Hengameh Abdi, Fereidoun Azizi, Farzad Hadaegh   +5 more
doaj   +1 more source

Testosterone is protective against impaired glucose metabolism in male intrauterine growth-restricted offspring. [PDF]

PLoS ONE, 2017
Placental insufficiency alters the intrauterine environment leading to increased risk for chronic disease including impaired glucose metabolism in low birth weight infants.
Suttira Intapad, John Henry Dasinger, Joel M Fahling, Miles A Backstrom, Barbara T Alexander   +4 more
doaj   +1 more source

Prevalence and factors associated with diabetes mellitus and impaired fasting glucose level among members of federal police commission residing in Addis Ababa, Ethiopia

BMC Endocrine Disorders, 2016
BackgroundThe prevalence of diabetes mellitus and factors associated with it, nowadays, are increasing in alarming rates among different occupational groups.
Tariku Tesfaye, Bilal Shikur, Tariku Shimels, N. Firdu   +3 more
semanticscholar   +1 more source

Predicting Metabolic Syndrome in Obese Children and Adolescents: Look, Measure and Ask

Obesity Facts, 2013
Objective: To verify in obese children whether or not the presence of i) high waist-to-height ratio (WHtR), ii) family history for type 2 diabetes (T2D) and iii) acanthosis nigricans (AN), singularly or together, might predict the occurrence of metabolic
Nicola Santoro, Alessandra Amato, Anna Grandone, Carmine Brienza, Piera Savarese, Nunzia Tartaglione, Pierluigi Marzuillo, Laura Perrone, Emanuele Miraglia del Giudice   +8 more
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Relationship between BMI and risk of impaired glucose tolerance and impaired fasting glucose in Chinese adults: a prospective study

BMC Public Health, 2023
Background Current studies in most Western countries have largely focused on body mass index (BMI) as an important risk factor for impaired glucose tolerance (IGT) and impaired fasting glucose (IFG), which have different pathophysiological bases.
Xin Zhang, Yankun Yue, Shaobo Liu, Xiangfeng Cong, Wenjuan Wang, Jianhong Li   +5 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Fasting plasma glucose levels and coronary artery calcification in subjects with impaired fasting glucose

Annals of Saudi Medicine, 2016
BACKGROUND: Prediabetes is associated with an increased risk of cardiovascular disease (CVD). While the association of impaired glucose tolerance with CVD has been shown in many studies, the relationship between impaired fasting glucose (IFG) and CVD ...
Young-Mi Eun, Sung-Goo Kang, Sang-Wook Song   +2 more
doaj   +1 more source