Results 41 to 50 of about 1,370,091 (259)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Impact Microindentation in Impaired Fasting Glucose and Diabetes

, 2022
Impact Microindentation in Impaired Fasting Glucose and ...
Julie Pasco (13077054), Pamela Godspower Rufus (13089843), Adolfo Diez-Perez (61539), Kara Kew (13073589), Muhammad Sajjad (722125), Lelia De Abreu (13364892), Mark Kotowicz (13079622)   +6 more
core  

Impaired fasting glucose and impaired glucose tolerance in rural central India: A study of prediabetes in the first degree relatives of patients with type 2 diabetes mellitus in a rural region of Malwa in Madhya Pradesh

National Journal of Physiology, Pharmacy and Pharmacology, 2017
Background: Prediabetes is a category of glucose tolerance representing an intermediate stage between normal glucose tolerance and diabetes and is characterized by impaired fasting glucose (IFG) and impaired glucose tolerance (IGT).
Abhilasha Dutta, Abhishek Kumar, S N Shukla, Amol Daniel   +3 more
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Assessment of prenatal and perinatal characteristics of pregnants with gestationel diabetes mellitus who have postnatal glucose abnormalities

Çukurova Üniversitesi Tıp Fakültesi Dergisi, 2013
Purpose: To examine the difference in terms of prenatal and perinatal characteristics between gestational diabetic (GDM) cases diagnosed with impaired fasting glucose (IFG)and impaired glucose tolerance (IGT) during early postpartum period.
Okan Bakiner, Emre Bozkirli, Hulya Serinsoz, Cagla Sariturk, Eda Ertorer   +4 more
doaj  

Results of DMVhi screening for undiagnosed type 2 diabetes, impaired fasting glucose and impaired glucose tolerance (March 2009-December 2012).

, 2015
RFG = repeat fasting glucose, IGT = impaired glucose tolerance, IFG = impaired fasting glucose, OGTT = oral glucose tolerance test. *Participants were not deemed to have completed screening if they did not return for required OGTT/RFG (n = 322) or did ...
Gerard Boran (724070), Abaigeal D. Jackson (724066), Margaret Sinnott (724064), Cecily Kelleher (724071), Bernadette Carr (724072), Brendan T. Kinsley (724065), Cathal Walsh (724067), Tony O’Grady (724068), John J. Nolan (198687), Peter Gaffney (724069)   +9 more
core   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Fasting plasma glucose levels and coronary artery calcification in subjects with impaired fasting glucose

Annals of Saudi Medicine, 2016
BACKGROUND: Prediabetes is associated with an increased risk of cardiovascular disease (CVD). While the association of impaired glucose tolerance with CVD has been shown in many studies, the relationship between impaired fasting glucose (IFG) and CVD ...
Young-Mi Eun, Sung-Goo Kang, Sang-Wook Song   +2 more
doaj   +1 more source

Comparison of characteristics between women with an impaired fasting glucose (IFG) and women with an impaired glucose tolerance (IGT) postpartum.

, 2016
Comparison of characteristics between women with an impaired fasting glucose (IFG) and women with an impaired glucose tolerance (IGT) postpartum.
Roland Devlieger (669006), Katrien Benhalima (2827148), Johan Verhaeghe (2827145), Katleen Jegers (2827142), Chantal Mathieu (93158)   +4 more
core   +1 more source