Results 31 to 40 of about 1,370,091 (259)

Assessment of cardiovascular risk factors in persons with impaired glucose tolerance [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2019
Introduction/Objective. The aim of the study was to determine the profile of cardiovascular risk factors in patients with impaired glucose tolerance (IGT) in comparison to patients with impaired fasting glucose (IFG). Methods.
Novaković Tatjana, Mirković Zlatica, Milošević Nenad, Živković Zorica, Mirić Dijana, Mirković Jana, Perić Vladan, Milošević Jovana   +7 more
doaj   +1 more source

The burden of diabetes mellitus and impaired fasting glucose in an urban population of Sri Lanka

, 2013
Aims: To describe the burden of diabetes mellitus and impaired fasting glucose in middle-aged residents (35-64 years) in an urban area of Sri Lanka. Methods: A cross-sectional survey was conducted in the Ragama Medical Officer of Health area, from which ...
Ranawake, U. K., Perera, S, Perera, S., Kato, N, Wickremasinghe, A. R., Kasturiratne, A, Warnakulasuriya, T, Gunasekara, D, Wijekoon, N, Kato, N., Medagoda, K., Kasturiratne, A., Medagoda, K, Wijekoon, N., Pinidiyapathirage, M. J., Takeuchi, F., Ranawaka, UK, Warnakulasuriya, T., Pinidiyapathirage, MJ, Gunasekara, D., Takeuchi, F, Wickremasinghe, AR   +21 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Long term prognostic implication of newly detected abnormal glucose tolerance among patients with stable cardiovascular disease: a population-based cohort study

Journal of Translational Medicine, 2021
Background Fasting plasma glucose (FPG) and 2-h post challenge plasma glucose (2 h-PCPG), whether as continuous or categorical variables, are associated with incident cardiovascular disease (CVD) and diabetes; however, their role among patients with ...
Maryam Kabootari, Samaneh Asgari, Seyedeh Maryam Ghavam, Hengameh Abdi, Fereidoun Azizi, Farzad Hadaegh   +5 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Multivariate logistic regression of risk factors for progression of impaired fasting glucose (IFG) to diabetes.

, 2023
Multivariate logistic regression of risk factors for progression of impaired fasting glucose (IFG) to diabetes.
Joseph Mkandawire (17054429), Lauren R. Rodgers (10052877), Rob C. Andrews (11303953), Amelia C. Crampin (9129871), Louis Banda (5632649), Moffat J. Nyirenda (9129874), Wisdom P. Nakanga (9351066), Andrew T. Hattersley (7654415)   +7 more
core   +1 more source

Relationship between BMI and risk of impaired glucose tolerance and impaired fasting glucose in Chinese adults: a prospective study

BMC Public Health, 2023
Background Current studies in most Western countries have largely focused on body mass index (BMI) as an important risk factor for impaired glucose tolerance (IGT) and impaired fasting glucose (IFG), which have different pathophysiological bases.
Xin Zhang, Yankun Yue, Shaobo Liu, Xiangfeng Cong, Wenjuan Wang, Jianhong Li   +5 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Predicting Metabolic Syndrome in Obese Children and Adolescents: Look, Measure and Ask

Obesity Facts, 2013
Objective: To verify in obese children whether or not the presence of i) high waist-to-height ratio (WHtR), ii) family history for type 2 diabetes (T2D) and iii) acanthosis nigricans (AN), singularly or together, might predict the occurrence of metabolic
Nicola Santoro, Alessandra Amato, Anna Grandone, Carmine Brienza, Piera Savarese, Nunzia Tartaglione, Pierluigi Marzuillo, Laura Perrone, Emanuele Miraglia del Giudice   +8 more
doaj   +1 more source