Results 91 to 100 of about 1,880,493 (302)

Prevalence of diabetes mellitus and impaired glucose tolerance in a rural community of Angola

Diabetology & Metabolic Syndrome, 2010
Background To determine the prevalence of diabetes mellitus (DM) and impaired glucose tolerance (IGT) in a rural community (Bengo) of Angola. Methods A random sample of 421 subjects aged 30 to 69 years (30% men and 70% women) was selected from three ...
Evaristo-Neto Antonio D, Foss-Freitas Maria, Foss Milton C   +2 more
doaj   +1 more source

Impaired fasting glucose and impaired glucose tolerance in rural population of Bangladesh

Bangladesh Medical Research Council Bulletin, 1970
The prevalence of type 2 diabetes is rapidly rising all over the world at an alarming rate. Over the past 30 years, the increase in prevalence is rising exponentially in South Asian region, data suggest a three fold increase (from 2.0 to 7.0%) in the urbanizing population of Bangladesh within 5 years.
Muhammad Abdur Rahim, Abul Kalam Azad Khan, Quamrun Nahar, S Ali, Akhtar Hussain   +4 more
openaire   +3 more sources

Variation of glucose tolerance in three patients of different age.

, 2014
Each patient had seven consecutive OGTTs with at least one diabetic result. Abbreviations: DGT diabetic glucose tolerance, IFG impaired fasting glucose, IGT impaired glucose tolerance, NGT normal glucose tolerance, OGTT oral glucose tolerance test.
Doris Staab (193176), Lutz Naehrlich (389423), Nicole Scheuing (494283), Christina Smaczny (494287), Sibylle Junge (494286), Gerd Dockter (494284), Julia M. Hermann (532292), Silke van Koningsbruggen-Rietschel (494289), Gabriela Thalhammer (494288), Reinhard W. Holl (445334), Manfred Ballmann (295167), Cordula Koerner-Rettberg (84944)   +11 more
core   +1 more source

Compact 9dBEs Enable Efficient and Precise Genome Editing in Mammalian Cells and In Vivo

Advanced Science, EarlyView.
As a compact type II‐D system, the Cas9d‐based platform holds great potential for in vivo applications. Through rational engineering, its derived base editors (9dBEs) enable efficient disease modeling while facilitating single‐vector AAV delivery for in vivo genome editing. These miniature tools offer a robust strategy for basic research and biomedical
Qingquan Xiao, Zhijin Tian, Luqi Weng, Kun Xu, Dingyi Han, Zhaowei Wu, Junnan Li, Shangpu Li, Qijing Zhang, Xiaohui Zhao, Guoling Li, Yinghui Wei, Zhen Gu   +12 more
wiley   +1 more source

Insulin sensitivity regulates cholesterol metabolism to a greater extent than obesity: lessons from the METSIM Study1

Journal of Lipid Research, 2010
Cholesterol synthesis is upregulated and absorption downregulated in insulin resistance and in type 2 dia-betes. We investigated whether alterations in cholesterol metabolism are observed across the glucose tolerance status, from normoglycemia through ...
Helena Gylling, Maarit Hallikainen, Jussi Pihlajamäki, Piia Simonen, Johanna Kuusisto, Markku Laakso, Tatu A. Miettinen   +6 more
doaj   +1 more source

Multivariable-adjusted odds ratios and 95% confidence intervals for having undiagnosed T2D, impaired glucose tolerance and impaired fasting glucose (compared with normoglycaemia) in the DMVhi study cohort.

, 2015
§ abdominal obesity defined as waist circumference of ≥80cm in females and ≥94cm in males,*NS = p value not significant (p>0.05). T2D = type 2 diabetes, IGT = impaired glucose tolerance, IFG = impaired fasting glucose, CIs = confidence intervals, BMI ...
Gerard Boran (724070), Abaigeal D. Jackson (724066), Margaret Sinnott (724064), Cecily Kelleher (724071), Bernadette Carr (724072), Brendan T. Kinsley (724065), Cathal Walsh (724067), Tony O’Grady (724068), John J. Nolan (198687), Peter Gaffney (724069)   +9 more
core   +1 more source

Inorganic Nanomaterials can Promote or Inhibit Tumor Metastasis Depending on Tumor Microenvironment Composition

Advanced Science, EarlyView.
As engineered nanomaterials gain prominence in cancer imaging and therapy, understanding their impact on tumor progression becomes increasingly critical. We demonstrate that gold and silica‐coated gold nanomaterials can either suppress or enhance breast cancer metastasis through distinct tumor microenvironment interactions, while identifying ...
Kiana Buttiens, Xiaoqi Zheng, Xueqi Fan, Mukaddes Izci, Christy Maksoudian, Irati Perez Gilabert, Tianjiao Chu, Filipa Goncalves, Jonas Dehairs, Johan Swinnen, Bella B. Manshian, Stefaan J. Soenen   +11 more
wiley   +1 more source

Repurposing FDA‐Approved Drugs to Inhibit Fungal PPTases for Broad‐Spectrum Synergy

Advanced Science, EarlyView.
Fungal secondary metabolites serve as crucial virulence effectors; however, the potential of their biosynthetic pathways as antifungal targets remains inadequately comprehended. Repurposed FDA‐approved drugs inhibit fungal PPTase (essential for secondary metabolism) in vivo.
Zili Song, Can Zhao, Qiaoling Wang, Hongjiao Zhang, Xiao Liu, Linqi Wang, Michael Bromley, Wen‐Bing Yin   +7 more
wiley   +1 more source

Changes in glucose homeostasis category by 2-hour oral glucose tolerance test.

, 2013
The trends for shifts in categories were not statistically different across study arms (P = 0.84, exact Jonckheere-Terpstra test). Abbreviations: DM, diabetes mellitus; IFG, impaired fasting glucose; IGT, impaired glucose tolerance; NGT, normal glucose ...
Donald P. Kotler (402144), Ya-Lin Chiu (402137), Jerry Ernst (402143), Kirsis Ham (402138), Martin Lesser (373029), Varalakshmi Muthukrishnan (402140), Henry N. Ginsberg (402141), Daniel Donovan (402142), Ellen Engelson (402139), Jeanine Albu (402136), Qing He (351975), Marshall J. Glesby (109595)   +11 more
core   +1 more source

Targeting the NR1D1–IGF2BP2–V‐ATPase Axis With Hybrid Nanovesicles Restores Macrophage Rhythms to Reverse Sepsis‐Induced Immunosuppression

Advanced Science, EarlyView.
Sepsis disrupts immune‐cell rhythms and weakens bacterial clearance. Biomimetic nanovesicles combining erythrocyte and inflammation‐activated macrophage membranes deliver siNR1D1 to dysfunctional macrophages, restoring the NR1D1–IGF2BP2–V‐ATPase pathway, circadian regulation, phagolysosomal acidification, and antimicrobial defense.
Lang Chen, Wenyi Lin, Lang Jiang, Xuehui Gao, Chenyan Yu, Jili Han, Zhenping Liu, Xuefeng Li, Mei He, Chang Li, Qilan Li, Chaoying Song, Jiqian Xu, You Shang   +13 more
wiley   +1 more source