Results 81 to 90 of about 1,880,493 (302)

Application and Single‐Cell Regulation Mechanism of Engineered EVs Combined With 4D‐Printed Hydrogel for Infected Burn Repair

Advanced Science, EarlyView.
4D bioprinted hydrogel loaded with FGF2‐modified extracellular vesicles (4D@F‐EVs) targets dermal fibroblasts and elevates local wound FGF2 levels via sustained release of F‐EVs. It activates PI3K‐Akt signaling, restores critical KGF+ fibroblast–KGFR+ keratinocyte crosstalk, enhances robust angiogenesis and collagen deposition to efficiently repair ...
Xiaomin Wang, Xiaoyan Li, Xiao Xu, Kelun Zhang, Fengjiao Yu, Zhen Shang, Nailong Pan, Junlin Lv, Yiwei Xu, Yan Tang, Liang Zhang, Xiaotong Li, Taoyi Wang, Jing Tao, Jiaxu Song, Mengyu Zhang, Xin Ma, Dan Han, Xiaoying Kong, Wenhua Xu   +19 more
wiley   +1 more source

Chinese herbal medicines for people with impaired glucose tolerance or impaired fasting blood glucose

, 2009
Around 308 million people worldwide are reported to have ’impaired glucose tolerance’. These individuals show higher than normal blood sugar (glucose) levels, but do not meet diagnostic criteria for having type 1 or type 2 diabetes.
Xun Li, Suzanne J Grant, Li, Xun, Jian Ping Liu, Dennis Chang, Alan Bensoussan, LiuSydney, Jianping, Grant, Suzanne J., Klupp, Nerida L., Hosen Kiat, Chang, Dennis Hsu-Tung, Nerida L Klupp, Bensoussan, Alan, Kiat, Hosen   +13 more
core   +1 more source

Deep Learning‐Driven Discovery and Engineering of an Efficient PETase for Depolymerization and Detoxification of PET Microplastics Under Physiological Conditions

Advanced Science, EarlyView.
A deep learning–driven pipeline mining 246 million protein sequences uncovers AhPETase, an evolutionarily distinct PET hydrolase. Engineered variant AhPETaseM1 degrades post‐consumer PET microplastics under physiological conditions and reverses microplasticinduced cytotoxicity in human lung and colon cells, establishing enzymatic microplastic ...
Yuxuan Wang, Shijie He, Yuheng Chang, Sheng Mao, Jianan Canal Li, Binbin Chen, Hongxun Gao, Mingchun Xu, Chenxu Liu, Yajie Wang   +9 more
wiley   +1 more source

Metabolic Syndrome in Turkish Adult Patients with Prediabetes: A Subgroup Analysis by Glucose Tolerance Status

Endocrinology Research and Practice
Objective: The current study aimed to investigate the prevalence of metabolic syndrome (MetS) among Turkish adults with prediabetes compared to normoglycemic individuals and to examine the distribution and characteristics of MetS across prediabetes ...
Hayri Bostan, Sema Hepşen, Ümran Gül, Pınar Akhanlı, Erman Çakal   +4 more
doaj   +1 more source

A Single A1C ≥ 6.5% Accurately Identifies Type 2 Diabetes/Impaired Glucose Tolerance in African Americans

Journal of Primary Care & Community Health, 2012
Objective: In 2010, the American Diabetes Association revised its criteria for the diagnosis of diabetes to include A1C ≥ 6.5%; however, this has remained controversial, particularly for African Americans. The objective of this pilot study was to examine
Carol J. Homko, Linda C. Zamora, Margaret M. Kerper, Maria Mozzoli, Karen Kresge, Guenther Boden   +5 more
doaj   +1 more source

Oral Glucose Tolerance Test among Adolescents with Impaired Fasting Blood Glucose [PDF]

, 2016
Background: Type 2 Diabetes Mellitus (DM) is emerging as a major health problem even amongst children and adolescents. The onset is usually preceded by period of impaired glucose metabolism known as Impaired Fasting Glucose (IFG) and or Impaired Glucose ...
Jaja, Tamunopriye, Okoh, Boma
core  

ROS‐Responsive Eye Drop for Controlled Release of 20‐Deoxyingenol Improves Diabetic Corneal Healing by Activating Macrophage Autophagy and Metabolic Reprogramming

Advanced Science, EarlyView.
Schematic illustration of ROS‐responsive TSPBA‐PVA microspheres loaded with 20‐deoxyingenol (TP/20‐DOI) for diabetic corneal wound healing: (a) fabrication and ROS‐triggered release; (b) autophagy activation and metabolic reprogramming in macrophages; (c) suppression of macrophage‐derived CXCL3/CXCL5, attenuation of neutrophil infiltration, and ...
Jiaxin Wu, Wanying Chen, Haijiang Qiu, Weihan Zheng, Ying Jiao, Jingheng Du, Zhudan Zhuang, Xing Hua, Jingyi Gu, Yuheng Liu, Zhaojin Li, Jingbin Xie, Hanxiao Sun, Huifei Lan, Xin Sun, Yunxia Xue, Ting Fu, Zhijie Li, Guobing Chen, Shiyu Li, Jun Liu   +20 more
wiley   +1 more source

Glycaemic changes in patients with chronic kidney disease

Nefrología (English Edition), 2016
In Argentina, there have been no studies aimed at establishing the prevalence of dysglycaemia (impaired fasting glucose [IFG], impaired glucose tolerance [IGT] and diabetes mellitus [DM]) in patients with chronic kidney disease (CKD).
Guillermo De’Marziani, Gervasio Soler Pujol, Liliana Miriam Obregón, Elisa Mabel Morales, Claudio Daniel Gonzalez, Luciana Gonzalez Paganti, Leonardo Cacciagiú, Graciela Lopez, Laura Schreier, Alicia Elbert   +9 more
doaj   +1 more source

The epidemiology of impaired glucose tolerance and hypertension

American Heart Journal, 1991
Epidemiologic research indicates that glucose intolerance and hypertension are interrelated phenomena, each powerfully predisposing to atherosclerotic cardiovascular disease. Both diabetic and hypertensive patients have greater amounts of atherogenic risk factors, including dyslipidemia, hyperuricemia, elevated fibrinogen, and left ventricular ...
W B, Kannel, P W, Wilson, T J, Zhang
openaire   +2 more sources

RSF1‐Dependent PAR Turnover Promotes 53BP1 Liquid Condensate Formation at DNA Damage Sites

Advanced Science, EarlyView.
At sites of DNA damage, RSF1 recruits PARG to accelerate PAR turnover, triggering a switch from PAR‐driven condensates to 53BP1 condensates. This condensate transition enables p53‐dependent gene transcription and coordinates the DNA damage response.
Yungyeong Heo, Yonghyeon Kim, Nangyeong Hwang, Gwanho Sung, Sujin Jo, Yeonhu Lee, Ho‐Chul Kang, Jae‐Ho Lee, Yong Won Choi, Hyeseong Cho, Sunwoo Min   +10 more
wiley   +1 more source