Results 121 to 130 of about 264,143 (351)

Overproduction of endothelin-1 impairs glucose tolerance but does not promote visceral adipose tissue inflammation or limit metabolic adaptations to exercise [PDF]

open access: bronze, 2019
Thomas J. Jurrissen   +16 more
openalex   +1 more source

Delta Opioid Receptors within the Cortico‐Thalamic Circuitry Underlie Hyperactivity Induced by High‐Dose Morphine

open access: yesAdvanced Science, EarlyView.
Morphine activates the excitatory cingulate cortex–intermediate rostrocaudal division of zona incerta (Cg‐ZIm) pathway to drive hyperlocomotion in mice. Inhibiting the Cg‐ZIm pathway attenuates both acute and chronic morphine‐induced hyperlocomotion, while its activation mimics morphine's motor effects.
Chun‐Yue Li   +13 more
wiley   +1 more source

Importance of OGTT for diagnosis of Diabetes in thalassemia major patients

open access: yesمجله دانشگاه علوم پزشکی گرگان, 2008
Background and Objective: Thalassemia major is a genetic disorder. Blood transfusion is critical for survival in these patients. Over the course of the past two and three decade’s hyper transfusion therapy in these patients has increased significant ...
Farzad Najafipour (MD)   +4 more
doaj  

Studies on the epidemiology of diabetes in Pacific populations [PDF]

open access: yes, 1984
Bibliography: leaves 192-207Thesis (M.D.) -- University of Adelaide, Dept.
King, Hilary Owen Meredith
core  

Hypothalamic Vitamin D Improves Glucose Homeostasis and Reduces Weight [PDF]

open access: yes, 2016
Despite clear associations between vitamin D deficiency and obesity and/or type 2 diabetes, a causal relationship is not established. Vitamin D receptors (VDRs) are found within multiple tissues, including the brain.
Arble, Deanna M.   +9 more
core   +4 more sources

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

open access: yesAdvanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou   +10 more
wiley   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang   +13 more
wiley   +1 more source

Disorders of carbohydrate metabolism in clinical practice

open access: yesMìžnarodnij Endokrinologìčnij Žurnal, 2017
Considering the prevalence of diabetes mellitus (DM), the possibility of early and rapid progress of complications, a large number of undiagnosed cases and disappointing forecasts of the World Health Organization on the prospects of DM spreading in the ...
V.I. Pankiv
doaj   +1 more source

Exogenous citrate impairs glucose tolerance and promotes visceral adipose tissue inflammation in mice [PDF]

open access: bronze, 2016
João Gabriel Bernardo Leandro   +8 more
openalex   +1 more source

Home - About - Disclaimer - Privacy