Results 131 to 140 of about 135,957 (263)

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

Advanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha, Ayushi Mairal, Shreya Mehrotra, Shiv K. Sarin, Ashok Kumar   +4 more
wiley   +1 more source

Food-Specific Morning and Night Intake Scores Are Associated with Impaired Glucose Tolerance during Pregnancy. [PDF]

J Nutr
Pleuss JD, Deierlein AL, Kleinberg S.
europepmc   +1 more source

LRRC4 Orchestrates AP2A1‐Containing Clathrin‐Coated Vesicles to Disrupt Mitochondrial Cristae and Restrict Glioblastoma Progression

Advanced Science, EarlyView.
LRRC4 suppresses GBM by regulating AP2A1‐containing Golgi‐derived clathrin‐coated vesicles. Low LRRC4 allows cytoplasmic AP2A1 to maintain mitochondrial fission‐fusion, MICOS integrity, and OXPHOS, promoting proliferation and invasion. High LRRC4 redirects AP2A1‐containing Golgi‐derived clathrin‐coated vesicles to mitochondria, disrupts MICOS, enhances
Yang Li, Cheng Huang, Liangqi Jiang, Zhen Li, Qing Liu, Minghua Wu   +5 more
wiley   +1 more source

Magnitude and Predictors of Subclinical Hypothyroidism in Individuals With Impaired Glucose Tolerance. [PDF]

Cureus
Chourey T, Khan Y, Pakhare AP, Singhai A, Parashar R, Joshi R, Meena M.   +6 more
europepmc   +1 more source

Neighborhood Deprivation and Racial Disparities in Early Pregnancy Impaired Glucose Tolerance. [PDF]

Int J Environ Res Public Health, 2023
Dolin CD, Mullin AM, Ledyard RF, Bender WR, South EC, Durnwald CP, Burris HH.   +6 more
europepmc   +1 more source

Artificial Host‐Guest Recognition Directs Glycometabolically Engineered Macrophages to Tumors

Advanced Science, EarlyView.
Glycoengineered supramolecular macrophages (GSAR‐M) are developed using glycometabolic labeling for bioorthogonal host‐guest tumor targeting. This engineering approach unexpectedly enhances macrophage migration, phagocytosis, and pseudopodia formation. Consequently, GSAR‐M demonstrate robust tumor‐targeting specificity, effectively arrest tumor growth,
Zhiqing Yang, Qian Cheng, Ziyi Wang, Jianwen Wei, Qun Guan, Huazhong Yu, Qingwen Zhang, Caixia Yin, Ruibing Wang   +8 more
wiley   +1 more source

Diagnostic differences in glycemic markers for detecting impaired glucose tolerance in Black African and White European men in the United Kingdom: The SOUL-DEEP cross-sectional study. [PDF]

J Diabetes Investig
Goff LM, Whelehan G, Bello T, Ghafar A, Ladwa M, Bodicoat DH, Stanners M, Amiel SA.   +7 more
europepmc   +1 more source

Proteomic signatures for identification of impaired glucose tolerance. [PDF]

Nat Med, 2022
Carrasco-Zanini J, Pietzner M, Lindbohm JV, Wheeler E, Oerton E, Kerrison N, Simpson M, Westacott M, Drolet D, Kivimaki M, Ostroff R, Williams SA, Wareham NJ, Langenberg C.   +13 more
europepmc   +1 more source

Unraveling Bone‐Skin Crosstalk Enables miRNA Nanoformulation for Cutaneous Neurovascular Reconstruction in Diabetic Mice

Advanced Science, EarlyView.
This study unravels that bone fracture accelerates diabetic wound healing by releasing exosomal microRNA (miR‐130b‐3p). To mimic this bone‐skin crosstalk, we engineered a self‐assembling agomir‐130b‐3p nanocomplex. Delivered via a photocrosslinkable hydrogel, this bio‐inspired therapy provides sustained localized agomir release.
Tao Shen, Hongdou Shen, Weiyue Wu, Zhuoying Jiang, Bin Liu, Yansi Xian, Rui Peng, An Yan, Yu Ben, Yong Shi, Xiang Chen, Baosheng Guo, Qing Jiang, Weijun Wang, Pingqiang Cai   +14 more
wiley   +1 more source

Impaired Glucose Tolerance and Altered Body Composition in Obese Young Adults: A Case-Control Study. [PDF]

Biomedicines
Mohamed-Mohamed H, Pardo-Moreno T, Jimenez-Palomares M, Perez-Ardanaz B, Sánchez-Lara EM, Vazquez-Lara MD, de La Mata-Fernandez M, García-Morales V, Ramos-Rodríguez JJ.   +8 more
europepmc   +1 more source