Results 91 to 100 of about 388,447 (291)
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Antenna pattern control using impedence surfaces [PDF]
During this research period, September 16, 1990 to March 15, 1991, a design method for selecting a low-loss impedance material coating for a horn antenna pattern control has been developed.
Balanis, Constantine A., Liu, Kefeng
core +1 more source
Unified force-impedance control
The International Journal of Robotics ResearchUnified force-impedance control (UFIC) aims at integrating the advantages of impedance control and force control. Compliance and exact force regulation are equally important abilities in modern robot manipulation. The developed passivity-based framework builds on the energy tank concept and is suitable for serial rigid and flexible-joint robots ...
Sami Haddadin, Erfan Shahriari
openaire +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Programmable electronic synthesized capacitance [PDF]
, 1987 A predetermined and variable synthesized capacitance which may be incorporated into the resonant portion of an electronic oscillator for the purpose of tuning the oscillator comprises a programmable operational amplifier circuit.
Kleinberg, Leonard L.
core +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Research on Robot Massage Force Control Based on Residual Reinforcement Learning
IEEE AccessTo address the problem that traditional force control methods have difficulty obtaining stable forces during a robot massage, a robot force control algorithm based on residual reinforcement learning is proposed.
Meng Xiao +4 more
doaj +1 more source
Microwave power transmission system wherein level of transmitted power is controlled by reflections from receiver [PDF]
, 1974 A microwave, wireless, power transmission system is described in which the transmitted power level is adjusted to correspond with power required at a remote receiving station.
Robinson, W. J., Jr.
core +1 more source