Results 101 to 110 of about 388,447 (291)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Adaptive Fractional Hybrid Impedance Control of Rotary Series Elastic Actuator in Flat Terrains

Advanced Intelligent Systems
This study presents a novel control approach, called adaptive fractional hybrid impedance control (AFH‐IC), for rotary series elastic actuators (RSEAs) operating in flat terrains, such as solid floors (hard), carpet (medium), and grass (soft).
Muhammed Özdemir, Zafer Bingül
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Research on fuzzy assisted interactive control of lower limb rehabilitation robot

Journal of Advanced Mechanical Design, Systems, and Manufacturing
In recent years, the number of lower limb injuries caused by stroke and traffic accidents has been increasing year by year, and the demand for rehabilitation equipment in the medical field is growing.
Zhijun WANG, Yunyi WANG, Mengxiang LI, Yue YANG   +3 more
doaj   +1 more source

Mode Switching Control Method for Man-Machine Collaborated Robotic Systems (Switching from Power-Assist Mode to Automatic Positioning Mode)

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2007
In the industrial world, not only autonomous machinery as industrial robots but also man-machine cooperative systems as power-assist systems have attracted special interest recently. Kondo, et al.
Susumu HARA
doaj   +1 more source

Impedance Control of Redundant Manipulators: Dissertation

, 2011
This thesis presents research work related to the impedance control of redundant manipulators. The main goal is to study the effects of redundancy on the dynamic behaviour of manipulators. Firstly, theoretical developments related to redundancy, dynamics and impedance control are presented in general form without restriction to any particular ...
openaire   +3 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Adaptive Robust Impedance Control of Grinding Robots Based on an RBFNN and the Exponential Reaching Law

Actuators
Given that grinding robots are easily affected by internal and external disturbances when machining complex surfaces with high precision, in this study, an adaptive robust impedance control method combining a radial basis function neural network (RBFNN ...
Lin Jia, Kun Chen, Zeyu Liao, Aodong Qiu, Mingjian Cao   +4 more
doaj   +1 more source

Scattering from coated structures and antenna pattern control using impedance surfaces, part A/B [PDF]

The scattering from coated, conducting structures, specifically the coated dihedral corner reflector configuration and the coated strip/plate configuration is examined.
Balanis, Constantine A., Liu, Kefeng, Polka, Lesley A.   +2 more
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source