Results 121 to 130 of about 147,312 (307)

Constant Force Control and Trajectory Planning of Multi-Axis Polishing Machine Using Active Disturbance Rejection Control and B-Spline Curve Algorithm

IEEE Access
The traditional force control strategy is on the basis of impedance control, which adjusts the position by adjusting the mechanical impedance between the end effector and the environment to achieve constant force control.
Qitao Tan, Mohd Ariffanan Mohd Basri, Jainbin Wang   +2 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Actuation and control for robotic physiotherapy [PDF]

, 2001
Over the last few years researchers have developed prototype robots that are capable of administering physiotherapy, however, these devices tend to be complex and expensive.
Richardson, Robert.C.
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Bounded Human–Robot Interaction Control Using Joint Torque Estimation From Electromyographic Signals

IEEE Access
Many of the most sophisticated human-robot interaction control schemes fall short when it comes to ensuring safe interactions, primarily because they do not generate bounded control actions.
Marco O. Mendoza-Gutierrez, Victor I. Ramirez-Vera, Isela Bonilla-Gutierrez, Emilio J. Gonzalez-Galvan, Ambrocio Loredo-Flores   +4 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Decentralised control for multi-channel active vibration isolation (in special Issue on dynamics and control of smart structures)

, 2001
This paper describes a theoretical and experimental investigation into an active four-mount vibration isolation system, in which electromagnetic actuators are installed in parallel with each of the four passive mounts placed between a three-dimensional ...
Brennan, M.J., Kim, Sang-Myeong, Elliott, S.J.   +2 more
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Identification of human limb stiffness in 5 DoF and estimation via EMG

, 2012
To approach robustness and optimal performance, biological musculo-skeletal systems can adapt their impedance while interacting with their environment. This property has motivated modern robotic designs including variable-impedance actuators and control
Bayer, Justin, Rüschen, Daniel, Vogel, Jörn, Lakatos, Dominic, van der Smagt, Patrick   +4 more
core  

High-Transparency Linear Actuator Using an Electromagnetic Brake for Damping Modulation in Physical Human–Robot Interaction

Journal of Sensor and Actuator Networks
Enhancing the transparency of high-transmission-ratio linear actuators is crucial for improving the safety and capability of high-force robotic systems having physical contact with humans in unstructured environments.
Zahid Ullah, Thachapan Sermsrisuwan, Khemwutta Pornpipatsakul, Ronnapee Chaichaowarat, Witaya Wannasuphoprasit   +4 more
doaj   +1 more source