Results 131 to 140 of about 147,312 (307)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Global impedance control of dual-arm manipulation for safe interaction

, 2012
The impedance control of dual-arm 7-DOF cooperative manipulators is considered in this paper. Global compliant behavior for the whole system is achieved using impedance at three levels, i.e. object, end-effector and body level.
FICUCIELLO, FANNY, H. SADEGHIAN, M. KESHMIRI, VILLANI, LUIGI   +3 more
core   +1 more source

Process control of robotic tile laying based on position-based impedance and fuzzy-adaptive contact force control

Journal of Intelligent Construction
Construction robots have garnered attention with the rapid development of construction automation. Such tiling robots can effectively improve the construction quality and efficiency.
Huixing Zhou, Shun Wang, Chongwen Xu, Haoyu Li   +3 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Multifrequency methods for Electrical Impedance Tomography

, 2015
Multifrequency Electrical Impedance Tomography (MFEIT) is an emerging imaging modality which exploits the dependence of tissue impedance on frequency to recover images of conductivity.
Malone, ER
core  

Modal Limit Cycle Control for Variable Stiffness Actuated Robots

, 2013
This paper presents a control approach to stabilize limit cycle motions along a mechanical mode of variable stiffness actuated (VSA) robots. Thereby, first a PD controller with gravity and Coriolis/centrifugal compensation shapes a desired dynamics ...
Garofalo, Gianluca, Gianluca Garofalo, Albu-Schäffer, Alin Olimpiu, Florian Petit, Petit, Florian, Dominic Lakatos, Alin Albu-Schaffer, Lakatos, Dominic, Ott, Christian, Christian Ott   +9 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Safe Acting and Manipulation in Human Environments: A Key Concept for Robots in our Society

, 2012
In this paper we review our work on safe acting and manipulation in human environments. In order for a robot to be able to safely interact with its environment it is primary to be able to react to unforeseen events in real-time on basically all levels of
Hirzinger, Gerd, Albu-Schäffer, Alin Olimpiu, Belder, Rico, Haddadin, Sami, Parusel, Sven   +4 more
core  

Analysis and control of resonant cavity flows [PDF]

, 2013
Recently, the trend for the internalisation of stores within an aircraft fuselage has led to a renewed interest in the field of cavity aero-acoustics.
Roberts, David
core  

Force and Trajectory Control of Industrial Robots in Stiff Contact

, 2013
Position-based force control is presented, incorporating compliance in the robot joints and possibly in a force- / torque-sensor and/or the environment. First, the total compliance is identified.
Michael Suppa, Suppa, Michael, Friedrich Lange, Wieland Bertleff, Bertleff, Wieland, Lange, Friedrich   +5 more
core   +1 more source