Results 41 to 50 of about 32,369 (300)

EXPERIMENTAL INVESTIGATION OF OPEN LOOP MULTI-STAGE IMPEDANCE PUMPING SYSTEM [PDF]

open access: yesJournal of Engineering Science and Technology, 2011
Impedance pump is a simple valveless pumping mechanism, where an elastic tube is joined to a more rigid one; a periodic asymmetrical pinching on the elastic tube will produce a unidirectional flow.
MUSHTAK AL-ATABI   +3 more
doaj  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Optimization of Multistep Cavity Configuration to Extend Absorption Bandwidth of Micro Perforated Panel Absorber

open access: yesArchives of Acoustics, 2018
Micro perforated panel (MPP) absorber is a new form of acoustic absorbing material in comparison with porous ones. These absorbers are considered as next generation ones and the best alternative for traditional porous materials like foams.
Iman FALSAFI, Abdolreza OHADI
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Methodology for Testing Acoustic Absorption of Lightweight Fabrics with 3D Microstructures Using Impedance Tube

open access: yesAcoustics
In this study, the limits of using the impedance tube, or Kundt tube, are examined using the two-microphone method to obtain the normal acoustic absorption coefficient when analyzing the sound absorption properties of lightweight acoustic fabrics ...
David Caballol   +2 more
doaj   +1 more source

Numerical Methodology to Obtain the Sound Absorption of Materials by Inserting the Acoustic Impedance

open access: yesArchives of Acoustics, 2021
Numerical models allow structural characteristics to be obtained by solving mathematical formulations. The sound absorption capacity of a material can be acquired by numerically simulating an impedance tube and using the method governed by ISO 10534-2 ...
Cláudia Ohana BORGES MENDES   +1 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Optimization of Nanowell-Based Label-Free Impedance Biosensor Based on Different Nanowell Structures

open access: yesBiosensors
Nanowell-based impedance-based label-free biosensors have demonstrated significant advantages in sensitivity, simplicity, and accuracy for detecting cancer biomarkers and macromolecules compared to conventional impedance-based biosensors.
Ali Fardoost   +2 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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