Results 61 to 70 of about 109,007 (299)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

In situ assessment of the normal incidence sound absorption coefficient of asphalt mixtures with a new impedance tube [PDF]

open access: yes, 2010
Normal incidence sound absorption coefficient of materials is usually calculated with the use of an impedance tube following the ISO 10534-2 international standard.
Freitas, Elisabete F.   +3 more
core  

Analogy electromagnetism-acoustics: Validation and application to local impedance active control for sound absorption [PDF]

open access: yes, 1998
An analogy between electromagnetism and acoustics is presented in 2D. The propagation of sound in presence of absorbing material is modeled using an open boundary microwave package.
Furstoss, M.   +2 more
core   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Sound Absorption of Wood-Wool Cement Absorbers

open access: yesبهداشت و ایمنی کار, 2023
Introduction: Wood-Wool Cement Panels (WWCPs) are environmentally friendly sound absorbers also used as heat, energy, and moisture insulators. WWCPs have suitable mechanical properties due to using Portland cement and wood strands as raw materials.
Ali Jafari   +4 more
doaj  

Impulse Generation by an Open Shock Tube [PDF]

open access: yes, 2008
We perform experimental and numerical studies of a shock tube with an open end. The purpose is to investigate the impulse due to the exhaust of gases through the open end of the tube as a model for a partially filled detonation tube as used in pulse ...
Browne, S. T.   +3 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Propagation of sound through the Earth's atmosphere. 1: Measurement of sound absorption in the air. 2: Measurement of ground impedance [PDF]

open access: yes
The fabrication of parts for the acoustic ground impedance meter was completed, and the instrument tested. Acoustic ground impedance meter, automatic data processing system, cooling system for the resonant tube, and final results of sound absorption in ...
Becher, J.   +2 more
core   +4 more sources

Home - About - Disclaimer - Privacy