Results 91 to 100 of about 99,909 (304)

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin   +2 more
wiley   +1 more source

Mesenchymal Stromal Cells and Cutaneous Wound Healing: A Comprehensive Review of the Background, Role, and Therapeutic Potential

open access: yesStem Cells International, 2018
Cutaneous wound repair is a highly coordinated cascade of cellular responses to injury which restores the epidermal integrity and its barrier functions.
Michael S. Hu   +4 more
doaj   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela   +13 more
wiley   +1 more source

Moral Repair and the Moral Saints Problem [PDF]

open access: yes, 2012
This article explores the forms of moral repair that the wrongdoer has to perform in an attempt to make amends for her past wrongdoing, with a focus on the issues of interpersonal moral repair; that is, what a wrongdoer can do to merit her victim‘s ...
Radzik, Linda
core   +1 more source

MintHint: Automated Synthesis of Repair Hints

open access: yes, 2013
Being able to automatically repair programs is an extremely challenging task. In this paper, we present MintHint, a novel technique for program repair that is a departure from most of today's approaches. Instead of trying to fully automate program repair,
Cadar C.   +7 more
core   +1 more source

Use of Symptomatic Drug Treatment for Fatigue in Multiple Sclerosis and Patterns of Work Loss

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe the use of central stimulants and amantadine for fatigue in MS and evaluate a potential association with reduced work loss in people with MS. Methods We conducted a nationwide, matched, register‐based cohort study in Sweden (2006 to 2023) using national registers with prospective data collection.
Simon Englund   +3 more
wiley   +1 more source

Cost Analysis of Series Systems with Different Standby Components and Imperfect Coverage

open access: yesOperations Research and Decisions, 2019
The authors calculate the steady-state availability and the cost-benefit analysis for three different systems with mixed standby (cold standby, warm standby) and imperfect coverage.
Mohamed El-Sherbeny, Zienab M. Hussien
doaj  

Mesenchymal Stem Cell Therapy for Nonmusculoskeletal Diseases: Emerging Applications

open access: yesCell Transplantation, 2009
Mesenchymal stem cells are stem/progenitor cells originated from the mesoderm and can different into multiple cell types of the musculoskeletal system.
Tom K. Kuo   +2 more
doaj   +1 more source

Repair-mediated duplication by capture of proximal chromosomal DNA has shaped vertebrate genome evolution.

open access: yesPLoS Genetics, 2009
DNA double-strand breaks (DSBs) are a common form of cellular damage that can lead to cell death if not repaired promptly. Experimental systems have shown that DSB repair in eukaryotic cells is often imperfect and may result in the insertion of extra ...
John K Pace   +3 more
doaj   +1 more source

Refocusing two qubit gates with measurements for trapped ions

open access: yes, 2016
Dynamical decoupling techniques are the method of choice for increasing gate fidelities. While these methods have produced very impressive results in terms of decreasing local noise and increasing the fidelities of single qubit operations, dealing with ...
Cohen, Daniel   +3 more
core   +1 more source

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