Results 121 to 130 of about 2,028,540 (336)

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

AI-Driven CBCT Analysis for Surgical Decision-Making and Mucosal Damage Prediction in Sinus Lift Surgery for patients with low RBH

open access: yesInternational Dental Journal
Background: Decision-making for maxillary sinus floor elevation (MSFE) surgery in patients with low residual bone height (
Yinxin Deng   +8 more
doaj   +1 more source

A nomogram to determine required seed air kerma strength in planar 131 Cesium permanent seed implant brachytherapy [PDF]

open access: yes, 2019
Purpose: Intraoperatively implanted Cesium-131 ( 131 Cs) permanent seed brachytherapy is used to deliver highly localized re-irradiation in recurrent head and neck cancers.
Bar-Ad, Voichita   +4 more
core   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Influence of parallel pins on the angle deviation for placement of dental implants: an in vitro study

open access: yesBMC Oral Health
The aim of the present study was to analyze and compare the angle deviation of two, four and six adjacent dental implants placed with and without straight parallel pins. Materials and Methods: Two hundred and forty (240) dental implants were selected and
Héctor González Menéndez   +7 more
doaj   +1 more source

Preemptive Ibuprofen and Orally Administered Dexamethasone for Prevention of Pain and Swelling following Implant Surgery

open access: yesRegeneration, Reconstruction & Restoration, 2016
Introduction: The post-operative pain and swelling are frequently observed after different surgical procedures. Orofacial pain management is a challenging topic for the dental-medical profession.
Fatemeh Amin   +2 more
doaj   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

Short-term Osteoclastic Activity Induced by Locally High Concentrations of Recombinant Human Bone Morphogenetic Protein–2 in a Cancellous Bone Environment [PDF]

open access: yes, 2009
Study Design. An experimental study investigating osteoclastic activity induced by rhBMP-2 in sheep. Objective. To examine the effects of increasing local rhBMP-2 concentration on osteoclastic response and peri-implant bone resorption.
Badura, Jeffrey   +5 more
core   +1 more source

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