Results 121 to 130 of about 677,246 (299)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Continuous Laparoscopic Closure of the Linea Alba with Barbed Sutures Combined with Laparoscopic Mesh Implantation (IPOM Plus Repair) As a New Technique for Treatment of Abdominal Hernias [PDF]

, 2017
Reiko Wießner, Thomas Vorwerk, Claudia Tolla-Jensen, Alexander Gehring   +3 more
openalex   +1 more source

Risk factors of local recurrence following implant-based breast reconstruction in breast cancer patients [PDF]

, 2021
M. Fujihara, Rie Yamasaki, Mitsuya Ito, Tadahiko Shien, Reina Maeda, Takanori Kin, Ayako Ueno, Yukiko Kajiwara, Kensuke Kawasaki, Kouichi Ichimura, Hiroya Mihara, Naritaka Kimura, Shoichiro Ohtani   +12 more
openalex   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Comparison of Bone Loss around Bone Platform Shift and Non-Bone Platform Shift Implants After 12 Months

Frontiers in Dentistry, 2015
Objectives: The aim of the present randomized clinical trial was to evaluate marginal bone loss around two types of implants modified at the neck area: Nobel Active and Nobel Replace Groovy, both manufactured by Nobel Biocare.
Amir Reza Rokn, Samareh Badri, Amir Alireza Rasouli Ghahroudi, Rebeca Manasheof, Mohamad Javad Kharazi Fard, Hamidreza Barikani   +5 more
doaj  

Representações sociais sobre a implantação dos colégios cívico-militares no Paraná: Social representations about the civic-military schools’ implantations in Paraná

, 2021
Everton de Souza
openalex   +1 more source

First-in-Human Implantation of a New Transcatheter Tricuspid Valve Replacement System

, 2023
Lars Søndergaard, Jacob Eifer Møller, Ole De Backer, Hasse Møller‐Sørensen, Yanping Cheng, Kasper Rossing, Morten Smerup, Arshad Quadri   +7 more
openalex   +1 more source

Biomarkers to Predict the Success of Treatment with the Intravitreal 0.19 mg Fluocinolone Acetonide Implant in Uveitic Macular Edema [PDF]

, 2022
Lucy J. Kessler, Grzegorz Łabuz, Gerd U. Auffarth, Ramin Khoramnia   +3 more
openalex   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Dental Implants [PDF]

International Journal of Biomaterials, 2013
Carlos Nelson Elias, Paulo G. Coelho
openaire   +3 more sources