Results 81 to 90 of about 527,039 (267)

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

FEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma, Jennifer R. Deuis, Xinying Jia, Theo Crawford, Sassan Rahnama, Eivind A. B. Undheim, Irina Vetter, Yanni K. ‐Y. Chin, Mehdi Mobli   +8 more
wiley   +1 more source

Improved tactile speech perception using audio-to-tactile sensory substitution with formant frequency focusing

Scientific Reports
Haptic hearing aids, which provide speech information through tactile stimulation, could substantially improve outcomes for both cochlear implant users and for those unable to access cochlear implants.
Mark D. Fletcher, Esma Akis, Carl A. Verschuur, Samuel W. Perry   +3 more
doaj   +1 more source

Effect of the computer-aided static navigation technique on the accuracy of bicortical mini-implants placement site for maxillary skeletal expansion appliances: an in vitro study

BMC Oral Health, 2023
The objective of the present study was to evaluate and compare the effect of the computer-aided static navigation technique on the accuracy of the maxillary skeletal expansion (MSE) appliances.
Paulina Rodríguez Torres, Elena Riad Deglow, Álvaro Zubizarreta-Macho, Georgia Tzironi, Héctor González Menéndez, Juan Lorrio Castro, Ana Belén Lobo Galindo, Sofía Hernández Montero   +7 more
doaj   +1 more source

A randomized clinical trial about presence of pathogenic microflora and risk of peri-implantitis: comparison of two different types of implant-abutment connections [PDF]

, 2017
OBJECTIVE: The aim of this in vivo study was to evaluate two different types of implant-abutment connections: screwed connection and cemented connection, analyzing peri-implant bacteria microflora as well as other clinical parameters.
De Angelis, Francesca, Di Carlo, Stefano, Mencio, Francesca, Papi, Piero, Pompa, Giorgio, Rosella, D.   +5 more
core  

110GHz fT Silicon Bipolar Transistors Implemented using Fluorine Implantation for Boron Diffusion Suppression

, 2006
This paper investigates how fluorine implantation can be used to suppress boron diffusion in the base of a double polysilicon silicon bipolar transistor and hence deliver a record fT of 110 GHz.
Alemanni, C., Ashburn, P., Bonar, J.M., El Mubarek, H.A.W., Fiore, L., Kham, M.N., Messina, A., Petralia, R., Ward, P.   +8 more
core   +1 more source

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

Molecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Elin Borgen, Cecilie Bendigtsen Schirmer, Bjørnar Gilje, Øystein Garred, Jon Lømo, Marius Stensland, Oddmund Nordgård, Ragnhild Sørum Falk, Randi R. Mathiesen, Hege G. Russnes, Jon Amund Kyte, Bjørn Naume   +13 more
wiley   +1 more source

Digital Planning for Immediate Implants in Anterior Esthetic Area: Immediate Result and Follow-Up after 3 Years of Clinical Outcome—Case Report

Dentistry Journal, 2023
In this case report, we demonstrate how the correct positioning of implants, associated with optimal gingival conditioning, and the correct choice of biomaterial can yield very predictable and fantastic aesthetic results.
Saulo Henrique Salviano, João Carlos Amorim Lopes, Igor da Silva Brum, Kelly Machado, Marco Tulio Pedrazzi, Jorge José de Carvalho   +5 more
doaj   +1 more source

Aesthetic satisfaction in lip and palate clefts: a comparative study between secondary and tertiary bone grafting [PDF]

, 2018
Lip and palate cleft represent one of the most frequently occurring congenital deformity, which includes dental anomalies, such as variation in tooth number and position.
Brauner, E, De Angelis, F, Di Carlo, S, Jamshir, S, Mezi, S, Pompa, G, Quarato, A, Tiroli, R C   +7 more
core   +1 more source

On‐treatment dynamics of circulating extracellular vesicles in the first‐line setting of patients with advanced non‐small cell lung cancer: the LEXOVE prospective study

Molecular Oncology, EarlyView.
The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina, Viviana Bazan, Nadia Barraco, Simona Taverna, Mauro Manno, Samuele Raccosta, Anna Paola Carreca, Marco Bono, Tancredi Didier Bazan Russo, Francesco Pepe, Pasquale Pisapia, Lorena Incorvaia, Giuseppe Badalamenti, Giancarlo Troncone, Umberto Malapelle, Daniele Santini, Antonio Russo, Antonio Galvano   +17 more
wiley   +1 more source

Music Perception Testing Reveals Advantages and Continued Challenges for Children Using Bilateral Cochlear Implants

Frontiers in Psychology, 2020
A modified version of the child’s Montreal Battery of Evaluation of Amusia (cMBEA) was used to assess music perception in children using bilateral cochlear implants.
Morrison M. Steel, Melissa J. Polonenko, Sara Giannantonio, Talar Hopyan, Blake C. Papsin, Blake C. Papsin, Karen A. Gordon, Karen A. Gordon   +7 more
doaj   +1 more source