Results 71 to 80 of about 9,393,515 (292)

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Implementation of TeamSTEPPS [PDF]

open access: yes, 2016
This scholarly project focused on implementing Team Strategies and Tools to Enhance Performance and Patient Safety (TeamSTEPPS) in an emergency room (ER).
Jones, Trynequa S
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Control-oriented implementation and model order reduction of a lithium-ion battery electrochemical model [PDF]

open access: yes, 2019
The use of electrochemical models makes it computationally intractable for online implementation as the model is subject to a complicated mathematical structure including partial-differential equations (PDE).
Li, Liuying   +3 more
core   +1 more source

Effectiveness and Safety of Nusinersen and Risdiplam in Spinal Muscular Atrophy: A Systematic Review

open access: yesAnnals of Clinical and Translational Neurology
Objective Spinal Muscular Atrophy (SMA) is a rare genetic disorder marked by progressive muscle weakness and mobility loss. It has a profound physical, emotional and social impact on patients and caregivers, requiring comprehensive medical and supportive
Amin Mehrabian   +9 more
doaj   +1 more source

Understanding collaborative care implementation in the Department of Veterans Affairs: core functions and implementation challenges

open access: yesBMC Health Services Research, 2017
Background The collaborative care model is an evidence-based practice for treatment of depression in which designated care managers provide clinical services, often by telephone.
Jessica M. Lipschitz   +6 more
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

The Implementation of Communicative Language Teaching Approach in a Secondary School in Surabaya [PDF]

open access: yes, 2014
This study is a qualitative study aimed to know the principles of CLT implemented and problems faced by a teacher in an English conversation class of eighth grades in S Secondary School. The data was taken through observation and interview.
Shinta, I. C. (Ina)   +1 more
core  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Numerical Implementation of Gradient Algorithms [PDF]

open access: yes, 2013
A numerical method for computational implementation of gradient dynamical systems is presented. The method is based upon the development of geometric integration numerical methods, which aim at preserving the dynamical properties of the original ordinary
A. Iserles   +6 more
core   +2 more sources

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