Results 71 to 80 of about 4,485,274 (315)

Part 8: Education, implementation, and teams: 2015 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations

, 2015
Current evidence demonstrates considerable variability in cardiac arrest survival in and out of hospital and, therefore, substantial opportunity to save many more lives.1–3 The Formula for Survival4 postulates that optimal survival from cardiac arrest ...
Nadkarni, Vinay M., Duff, J., Jon C. Rittenberger, Lang, Eddy, Lang, E., Aaron J. Donoghue, Koenraad G. Monsieurs, Iwami, Taku, Billi, John E., Leary, M., Steven C. Brooks, Judith C. Finn, Ming-Ju Hsieh, Greif, R., Yeung, J., Bhanji, F., Cheng, A., Billi, John E, Elaine Gilfoyle, Lockey, A., Matthew Huei-Ming Ma, Andrew Lockey, Janet E. Bray, Robert Frengley, Finn, J., Dana P. Edelson, Lockey, Andrew, Robert Greif, Mary E. Mancini, Vinay M. Nadkarni, Fischer, H., Huei-Ming Ma, Matthew, Eddy Lang, Greif, Robert, Nadkarni, V., Monsieurs, K., David A. Kloeck, Taku Iwami, Iwami, T., Bhanji, Farhan, Bigham, Blair, Mancini, Mary E., Brooks, S., Theresa M. Olasveengen, McNeil, Mary Ann, Jan Breckwoldt, Bray, Janet, Adam Cheng, Finn, Judith C, Patrick Ko, Traci A. Wolbrink, Edelson, D., Schultz, R., Mancini, M., John E. Billi, Hsieh, M., Olasveengen, T., Zuzana Triska, Mancini, Mary E, Breckwoldt, J., Jonathan P. Duff, Robert D. Schultz, Dion Stub, McNeil, M., Rittenberger, J., Nadkarni, Vinay M, Stub, D., Yang, C., Frengley, Robert, Koenraad Monsieurs, Donoghue, A., Joyce Yeung, Kloeck, D., Frengley, R., Finn, Judith C., Blair Bigham, Henrik Fischer, Bigham, B., Wolbrink, T., Gilfoyle, E., Monsieurs, Koen, Billi, J., Monsieurs, Koenraad, Ma, Matthew Huei-Ming, Mary Ann McNeil, and on behalf of the Education, Implementation, and Teams Chapter Collaborators, Ma, M., Chih-Wei Yang, Ko, P., Triska, Z., Farhan Bhanji, Marion Leary   +91 more
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Theory and behaviour change techniques informing strategies to improve recruitment to clinical trials: a systematic review of randomised evaluations

Trials
Introduction Efficiently meeting recruitment targets is foundational to clinical trial success. Past reviews on improving recruitment efficiency have highlighted only a few evidence-supported strategies; some of which may be context-specific, infeasible,
Natasha Hudek, Kelly Carroll, Seana N. Semchishen, Justin Presseau, Katie Gillies, Jeremy Grimshaw, Dean A. Fergusson, Ian D. Graham, Monica Taljaard, Jamie C. Brehaut   +9 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Predicting suicide death among veterans after psychiatric hospitalization using transformer based models with social determinants and NLP

Scientific Reports
Predictions of suicide death of patients discharged from psychiatric hospitals (PDPH) can guide intervention efforts including intensive post-discharge case management programs, designed to reduce suicide risk among high-risk patients. This study aims to
Zhichao Yang, Avijit Mitra, Wen Hu, Dan Berlowitz, Hong Yu   +4 more
doaj   +1 more source

An Experiment on Nash Implementation [PDF]

, 2001
We perform an experimental test of a modification of the controversial canonical mechanism for Nash implementation, using three subjects in non-repeated groups, as well as three outcomes, states of nature, and integer choices. We find that this mechanism
Cabrales, Antonio, Charness, Gary B, Corchón, Luis C., Charness, Gary, Corchon, Luis C   +4 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Progress report on implementation aspects of the Thames River Basin water management study

, 1978
This progress report identifies the preliminary stance adopted by the Thames River Implementation Committee towards the 29 recommendations contained in the 1975 Thames River Basin Water Management Study and outlines the activities carried out by the ...
Thames River Implementation Committee
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Progress report 3 Thames River Implementation Committee

, 1981
This third TRIC Progress Report outlines the revised status of each of the recommendations since the time of the first Progress Report, provides an overview of the 1980/81 work program, and provides a program status update for the 1981/82 program.
Thames River Implementation Committee
core