Results 81 to 90 of about 2,643,904 (299)

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Use of the Internet to Counter the Appeal of Extremist Violence. Conference Summary & Follow-up/ Recommendations

Perspectives on Terrorism, 2012
by the United Nations Counterterrorism Implementation Task Force (CTITF), Working Group on Use of the Internet for Terrorist Purposes  Riyadh, 24 - 26 January 2011. 
(CTITF) United Nations Counterterrorism Implementation Task Force
doaj  

Automated tests for diagnosing and monitoring cognitive impairment: a diagnostic accuracy review

Health Technology Assessment, 2016
Background: Cognitive impairment is a growing public health concern, and is one of the most distinctive characteristics of all dementias. The timely recognition of dementia syndromes can be beneficial, as some causes of dementia are treatable and are ...
Rabeea’h W Aslam, Vickie Bates, Yenal Dundar, Juliet Hounsome, Marty Richardson, Ashma Krishan, Rumona Dickson, Angela Boland, Eleanor Kotas, Joanne Fisher, Sudip Sikdar, Louise Robinson   +11 more
doaj   +1 more source

Cooperative Demand Response Framework for a Smart Community Targeting Renewables: Testbed Implementation and Performance Evaluation [PDF]

, 2020
Carlos Cruz, Esther Palomar, Ignácio Bravo, Alfredo Gardel   +3 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Embedding consumer and community involvement in antenatal healthcare research: A methodological approach and perspectives of culturally and linguistically diverse women in Australia

Research Involvement and Engagement
Background Consumer and Community Involvement (CCI) in healthcare research ensures that the needs of target populations are met through active collaboration between consumers, communities, and researchers. For culturally and linguistically diverse (CALD)
Bonnie R. Brammall, Rebecca L. Madill, Rhonda M. Garad, Bao N. Nguyen, Nitya Nagesh, Cheryce L. Harrison   +5 more
doaj   +1 more source

Effectiveness and safety of natural mineral water rich in magnesium and sulfates for the intestinal function

Медицинский совет, 2016
A randomized, placebo-controlled, double-blind trialObjective. The present randomized placebo-controlled double-blind trial was conducted to examine whether natural mineral water with a high content of magnesium sulfate and sodium sulfate (Donat Mg ...
Gordana Bote, Alyaz Chokh, Annegret Auinger   +2 more
doaj   +1 more source

Parents’ Perceptions Regarding the Implementation of a Physical Therapy Stimulation Program for Children with Disabilities in Bolivia: A Qualitative Study [PDF]

, 2020
Sagrario Pérez‐de la Cruz, Ivonne Ramírez   +1 more
openalex   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source