Results 101 to 110 of about 6,608,154 (291)

Developing preparedness for flexible delivery of training in enterprises

, 2002
On a basis of research and literature review, Smith, in 2001, suggested a model for the development of preparedness of learners and their workplaces to support the flexible delivery of training in enterprises.
Robertson, Ian, Smith, Peter, Wakefield, Lyn   +2 more
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Trends in Anemia Prevalence Among Indian Women Using Revised WHO Hemoglobin Cutoffs: Insights From Repeated Cross-Sectional Surveys (1998–2019)

Anemia
Conclusion: This study highlights a decline in anemia prevalence, particularly in severe cases during pregnancy. Anemia reduction efforts must rely on country-specific data, especially on the Hb distribution against the background of ferritin level ...
Anuj Kumar Pandey, Diksha Gautam, Benson Thomas M., Sutapa Bandyopadhyay Neogi   +3 more
doaj   +1 more source

Evaluation of the learning and skills measure [PDF]

, 2010
In April 2009, the Department for Children, Education, Lifelong Learning and Skills commissioned York Consulting, in association with Old Bell 3, to undertake research to inform the implementation of the Learning and Skills Measure. The broad aims of the
Magee, Andrew
core  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

One size doesn’t fit all: methodological reflections in conducting community-based behavioural science research to tailor COVID-19 vaccination initiatives for public health priority populations

BMC Public Health
Background Promoting the uptake of vaccination for infectious diseases such as COVID-19 remains a global challenge, necessitating collaborative efforts between public health units (PHUs) and communities.
Guillaume Fontaine, Maureen Smith, Tori Langmuir, Karim Mekki, Hanan Ghazal, Elizabeth Estey Noad, Judy Buchan, Vinita Dubey, Andrea M. Patey, Nicola McCleary, Emily Gibson, Mackenzie Wilson, Amjad Alghamyan, Kateryna Zmytrovych, Kimberly Thompson, Jacob Crawshaw, Jeremy M. Grimshaw, Trevor Arnason, Jamie Brehaut, Susan Michie, Melissa Brouwers, Justin Presseau   +21 more
doaj   +1 more source

Personnel time requirements for mobile chest X-ray screening for TB

IJTLD Open
BACKGROUND: Community-based active case finding (ACF) using chest X-ray (CXR) is effective for early TB detection, but implementation is limited by high resource demands.
T.S. Johnson, J. Kakeeto, D. Isooba, S. Birabwa, J. Magezi, W. Kamya, R. Okura, I. Naluyima, A. Nalutaaya, P.J. Kitonsa, E.A. Kendall, A. Katamba, D.W. Dowdy   +12 more
doaj   +1 more source

A method to reduce imbalance for site-level randomized stepped wedge implementation trial designs

Implementation Science, 2019
Background Controlled implementation trials often randomize the intervention at the site level, enrolling relatively few sites (e.g., 6–20) compared to trials that randomize by subject.
Robert A. Lew, Christopher J. Miller, Bo Kim, Hongsheng Wu, Kelly Stolzmann, Mark S. Bauer   +5 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Developing a quality assurance model for small military institutions [PDF]

, 2008
Bahrain Defence Force (BDF) has a limited manpower, land to manoeuvre and resources. This reason has led the researcher to investigate the effective dimensions of discovering a model for quality assurance in higher education within a military context in ...
Bahzad, Y, Irani, Z
core