Results 111 to 120 of about 2,679,990 (305)

[Texas Department of Transportation] Research and Technology Implementation Office: University Handbook

, 2010
This is a research manual designed by the Research and Technology Implementation Office (RTI) to present program policies and establish procedures for universities involved in research with the Texas Department of Transportation (TxDOT)
Texas. Department of Transportation. Research and Technology Implementation Office.
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A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Trends in Anemia Prevalence Among Indian Women Using Revised WHO Hemoglobin Cutoffs: Insights From Repeated Cross-Sectional Surveys (1998–2019)

Anemia
Conclusion: This study highlights a decline in anemia prevalence, particularly in severe cases during pregnancy. Anemia reduction efforts must rely on country-specific data, especially on the Hb distribution against the background of ferritin level ...
Anuj Kumar Pandey, Diksha Gautam, Benson Thomas M., Sutapa Bandyopadhyay Neogi   +3 more
doaj   +1 more source

Evaluating the implementation of a prisoner re-entry initiative for individuals with opioid use and mental health disorders: Application of the consolidated framework for implementation research in a cross-system initiative

, 2019
Given the interrelated nature of opioid use, criminal justice interaction, and mental health issues, the current opioid crisis has created an urgent need for treatment, including medication assisted treatment, among justice-involved populations ...
Pinals, Debra A., Andre, Michael, Gaba, Ayorkor, Kubiak, Sheryl, Hanna, Julie, Smelson, David A., Pasman, Emily   +6 more
core   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Human papillomavirus awareness and vaccination willingness among adults in Madagascar: a cross-sectional study

BMC Women's Health
Disease awareness is key to utilising healthcare services, including vaccinations. Madagascar, with high human papillomavirus (HPV) prevalence (> 36%), marked cervical cancer rates, and low general routine vaccination coverage, faces major challenges in ...
Aaron Remkes, Alexina Zafinimampera, Olivette Totofotsy, Fesia Elveric Ratiaharison, Haingoniavo Garcia Rambeloson, Elly Daus, Myriam Lassmann, Alexandra Schmidt, Fiona Franz, Pia Rausche, Jana Hey, Tiana Randrianarisoa, Tahinamandranto Rasamoelina, Irina Kislaya, Diavolana Andrianarimanana, Jürgen May, Valentina Marchese, Rivo Andry Rakotoarivelo, Daniela Fusco   +18 more
doaj   +1 more source

FHWA research and development implementation catalog.

Cover title.Mode of access ...
United States. Federal Highway Administration. Implementation Division.
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Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

One size doesn’t fit all: methodological reflections in conducting community-based behavioural science research to tailor COVID-19 vaccination initiatives for public health priority populations

BMC Public Health
Background Promoting the uptake of vaccination for infectious diseases such as COVID-19 remains a global challenge, necessitating collaborative efforts between public health units (PHUs) and communities.
Guillaume Fontaine, Maureen Smith, Tori Langmuir, Karim Mekki, Hanan Ghazal, Elizabeth Estey Noad, Judy Buchan, Vinita Dubey, Andrea M. Patey, Nicola McCleary, Emily Gibson, Mackenzie Wilson, Amjad Alghamyan, Kateryna Zmytrovych, Kimberly Thompson, Jacob Crawshaw, Jeremy M. Grimshaw, Trevor Arnason, Jamie Brehaut, Susan Michie, Melissa Brouwers, Justin Presseau   +21 more
doaj   +1 more source