Results 101 to 110 of about 1,647,499 (256)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Adapting the 2022 WHO verbal autopsy tool for use in Lagos State, Nigeria: insights from the LVASA-SRS project

BMC Research Notes
Objective Accurate and routine cause-of-death data are essential for health planning, yet many low- and middle-income countries lack comprehensive systems for such data, resulting in undocumented maternal and perinatal deaths.
Adeyemi Okunowo, Uchenna Gwacham-Anisiobi, Ndubuisi Ezumezu, Hameed Adelabu, Adedoyin Ogunyemi, Teniola Lawanson, Brenda Isikekpei, Bosede B. Afolabi, Aduragbemi Banke-Thomas   +8 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Cost-Effectiveness of Interventions Related to the Treatment of Women With Polycystic Ovary Syndrome: A Scoping Review

International Journal of Women's Health
Emily Joy Callander,1,2 Yanan Hu,1 Alayna Carrandi,2 Chau Thien Tay,2 Aya Mousa,2 Helena Teede2 1School of Public Health, University of Technology Sydney, Sydney, NSW, Australia; 2Monash Centre for Health Research and Implementation, Monash University ...
Callander EJ, Hu Y, Carrandi A, Tay CT, Mousa A, Teede H   +5 more
doaj  

A scoping review exploring women’s experiences of cardiometabolic pregnancy complications and future cardiovascular health implications

npj Cardiovascular Health
Women who develop cardiometabolic pregnancy complications including gestational diabetes mellitus (GDM), hypertensive disorders of pregnancy (HDP), fetal growth restriction (FGR) and preterm birth (PTB) are at increased risk of type 2 diabetes and ...
Wentong Xu, Monique Wisnewski, Caroline Kindsvater, Helena Teede, Lisa J. Moran, Sarah Lang   +5 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Implementation Lessons for Research and Practice [PDF]

Global Implementation Research and Applications, 2021
Bertram, Rosalyn, Blase, Karen, Breitenstein, Susie, Covell, Nancy, Edwards, Dan, Engell, Thomas, Kerns, Suzanne E. U., Sarkies, Mitchell, Scherpbier, Robert, Waldherr, Karin, Williams, Caitlin   +10 more
openaire   +2 more sources

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source